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Article
ARMC5 is not implicated in familial hyperaldosteronism type II (FH-II)
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Article
Treatment of primary aldosteronism is associated with a reduction in the severity of obstructive sleep apnoea
Obstructive sleep apnoea (OSA) is known to commonly co-exist with primary aldosteronism (PA), but it is unknown if treatment of PA improves sleep apnoea parameters in these patients. We therefore aimed to dete...
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Article
Salt, aldosterone and hypertension
Clinical studies have shown that aldosterone and salt are independently related to hypertension, cardiovascular morbidity and mortality. More recently, studies in humans have demonstrated that, similarly to an...
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Article
Unilateral adrenalectomy improves urinary protein excretion but does not abolish its relationship to sodium excretion in patients with aldosterone-producing adenoma
Experimental and human data suggest that adverse cardiovascular (CV) and renal effects of aldosterone excess are dependent on concomitant dietary salt intake. Increased urinary protein (Uprot) is an early sign...
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Article
Further study of chromosome 7p22 to identify the molecular basis of familial hyperaldosteronism type II
Familial hyperaldosteronism type II (FH-II) is an inherited form of hyperaldosteronism associated with hypertension in most patients. The mutations that cause FH-II are unknown, but linkage analysis has mapped...
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Article
4.5 Linkage of Familial Hyperaldosteronism Type II at Chromosome 7p22 in Two Italian Families
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Chapter
Sodium Channel Specific Neurotoxins: Recent Advances in the Understanding of Their Molecular Mechanisms
The voltage-dependent sodium channel is a large transmembrane glycoprotein that mediates the sodium current during the action potential, a characteristic property of excitable cells (Hodgkin and Huxley 1952). A n...
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Article
Intrahepatic bile duct strictures after human orthotopic liver transplantation
One of 55 patients transplanted for sclerosing cholangitis during the cyclosporin-steroid era (March 1980–June 1986) developed intrahepatic biliary strictures in the absence of allograft rejection within the 1...
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Chapter
Certain Surface Properties of Isolated and Cultured Cerebellar Cells
In order to further the understanding of the biochemical properties of the different neural cell types we have been engaged over the last few years in studies aimed at the separation and characterization of pe...
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Article
Cytotoxic T-cell responses to H-Y:Ir genes and associative antigens map inH-2
The secondary cytotoxic responses to the male-specific antigen (H-Y) in mice showH-2 restriction so that the cytotoxic female cell must share the K- and/or D-end antigen with the male target cells. The associatio...