51 Result(s)

Article

Calcifediol or vitamin D to optimize vitamin D status: Reply to letter of M Sosas

R. Bouillon, J. M. Quesada-Gomez in Osteoporosis International (2019)

Article

Vitamin D and cardiovascular disorders

Vitamin D is necessary for bone health but may also have many extra-skeletal effects. The vitamin D endocrine system has major effects on gene and protein expression in many cells and tissues related to the ca...

R. Bouillon in Osteoporosis International (2019)

Article

Is calcifediol better than cholecalciferol for vitamin D supplementation?

Modest and even severe vitamin D deficiency is widely prevalent around the world. There is consensus that a good vitamin D status is necessary for bone and general health. Similarly, a better vitamin D status ...

J. M. Quesada-Gomez, R. Bouillon in Osteoporosis International (2018)

Article

Associations of total and free 25OHD and 1,25(OH)₂D with serum markers of inflammation in older men

Vitamin D is hypothesized to suppress inflammation. We tested total and free vitamin D metabolites and their association with inflammatory markers. Interleukin-6 levels were lower with higher 25-hydroxyvitamin...

P. Srikanth, R. F. Chun, M. Hewison, J. S. Adams, R. Bouillon… in Osteoporosis International (2016)

Article

PDLIM2 expression is driven by vitamin D and is involved in the pro-adhesion, and anti-migration and -invasion activity of vitamin D

1Alpha,25-dihydroxyvitamin D₃ [1,25(OH)₂D₃], the biologically active form of vitamin D_3, is a pleiotropic hormone that exerts its effects on a wide range of tissues, resulting in different biological responses su...

E Vanoirbeek, G Eelen, L Verlinden, G Carmeliet, C Mathieu, R Bouillon… in Oncogene (2014)

Article

Vitamin D: do we get enough?

On September 29, 2011, acknowledged experts in the field of vitamin D, mainly European, were brought together in order to discuss the recent scientific advances in relation to vitamin D: the current requiremen...

E. M. Brouwer-Brolsma, H. A. Bischoff-Ferrari, R. Bouillon… in Osteoporosis International (2013)

Article

Sex steroids during bone growth: a comparative study between mouse models for hypogonadal and senile osteoporosis

In this study, the role of disturbed bone mineral acquisition during puberty in the pathogenesis of osteoporosis was studied. To this end, a mouse model for senile and hypogonadal osteoporosis was used. Longit...

J. Ophoff, K. Venken, F. Callewaert, S. Boonen, R. Bouillon… in Osteoporosis International (2009)

Article

Expression of the BRCA1-interacting protein Brip1/BACH1/FANCJ is driven by E2F and correlates with human breast cancer malignancy

Mutations in the BRCA1-interacting DEAH helicase Brip1 confer an increased risk of breast cancer. In the present study we aimed to unravel the transcriptional control of Brip1 and to determine its expression l...

G Eelen, I Vanden Bempt, L Verlinden, M Drijkoningen, A Smeets, P Neven… in Oncogene (2008)

Article

Calcitriol Improves Streptozotocin-induced Diabetes and Recovers Bone Mineral Density in Diabetic Rats

Vitamin D analogs exert a preventative effect on experimental diabetes, but whether or not they are able to halt progress of established diabetes is not yet known. Moreover, it is widely accepted that diabetes...

J. del Pino-Montes, G. E. Benito, M. P. Fernández-Salazar… in Calcified Tissue International (2004)

Article

Vitamin D Deficiency in Guinea Pigs: Exacerbation of Bone Phenotype During Pregnancy and Disturbed Fetal Mineralization, with Recovery by 1,25(OH)2D3 Infusion or Dietary Calcium-Phosphate Supplementation

Vitamin D (D) deficiency during human pregnancy appears to disturb fetal growth and mineralization, but fetal development is normal in D-deficient rats and vitamin D receptor gene-ablated mice. We used the gui...

K. Rummens, R. Bree, E. Herck, Z. Zaman, R. Bouillon… in Calcified Tissue International (2002)

Article

The Estrogen Receptor Ligand ICI 182,780 Does Not Impair the Bone-Sparing Effects of Testosterone in the Young Orchidectomized Rat Model

L. Vandenput, J.V. Swinnen, E. Van Herck, A. Verstuyf… in Calcified Tissue International (2002)

Chapter

Androgens, Skeletal Homeostasis, and Osteoporosis

Osteoporosis is a major health problem, not only in women but also in men. The skeletal effects of estrogen deficiency and replacement therapy are well established in women. More recently, it has also been rec...

D. Vanderschueren, L. Vandenput, A. Verstuyf… in Androgens and Androgen Receptor (2002)