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  1. No Access

    Chapter and Conference Paper

    A High-Resolution Tile-Based Approach for Classifying Biological Regions in Whole-Slide Histopathological Images

    Computational analysis of histopathological whole slide images (WSIs) has emerged as a potential means for improving cancer diagnosis and prognosis. However, an open issue relating to the automated processing ...

    R. A. Hoffman, S. Kothari, J. H. Phan… in The International Conference on Health Inf… (2014)

  2. No Access

    Chapter and Conference Paper

    Rolle der selektiv leukozytären iNOS-Expression bei der Genese der septischen Atonie des Gastrointestinaltraktes

    Background: Lipopolysaccharide (LPS) induces massive muscularis inflammation in the small intestine that has been associated with iNOS expression and ileus. Aims: The objective of the study was t...

    Dr. med. Andreas Türler, B. A. Moore, J. C. Kalff… in Chirurgisches Forum 2002 (2002)

  3. No Access

    Article

    Effect of annealing on microstructure, residual stress, and hardness of Al–Ti multilayered films

    Al–Ti multilayered films (12 at.% Ti) with bilayer period of 16 nm were deposited by magnetron sputtering. The films were annealed in vacuum at 350 or 400 °C between 2 and 24 h. During annealing, a diffusion-c...

    R. Mitra, A. Madan, R. A. Hoffman, W.-A. Chiou… in Journal of Materials Research (2001)

  4. No Access

    Article

    Effect of process variables on the structure, residual stress, and hardness of sputtered nanocrystalline nickel films

    Nanocrystalline nickel films of about 0.1 μm thickness grown by sputtering with and without substrate bias possessed average grain sizes of 9–25 nm. Variation in substrate bias at room and liquid nitrogen temp...

    R. Mitra, R. A. Hoffman, A. Madan, J. R. Weertman in Journal of Materials Research (2001)

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    Article

    Enhanced cytolytic activity of intestinal intraepithelial lymphocytes in patients with Crohn’s disease

    Background and aims: Dysfunction of the immune system with inappropriate responses of lymphocytes to various antigens has been implicated in the development of Crohn’s disease. Therefore, the functional and phe...

    N. C. Nüssler, B. Stange, R. A. Hoffman, W. H. Schraut… in Langenbeck's Archives of Surgery (2000)

  6. No Access

    Article

    Effect of Annealing on Microstructure and Properties of Al−Ti Multilayered Films

    Al-Ti multilayered films were deposited by magnetron sputtering of Al and Ti targets on to Si (100) or NaCl substrates. The bi-layer thickness was 16 nm with Ti constituting 12% of the total thickness. The fil...

    R. Mitra, A. Madan, R. A. Hoffman, W. A. Chiou… in MRS Online Proceedings Library (1999)

  7. No Access

    Article

    Elastic rebound between an indenter and a layered specimen: Part II. Using contact stiffness to help ensure reliability of nanoindentation measurements

    Measurement of nanoindentation hardness and modulus relies on the determination of the projected area of the indent, A, usually done by one of two methods: (1) indirectly, based on depth of indentation and cal...

    K. B. Yoder, D. S. Stone, R. A. Hoffman, J. C in Journal of Materials Research (1998)

  8. No Access

    Chapter and Conference Paper

    Gleichzeitige funktionelle Aktivierung intraepithelialer Lymphozyten und verstärkte Expression der induzierbaren Nitric Oxide Synthase in der Dünndarmmukosa während Septikämie

    Lipopolysaccharide (LPS) aus der Zellwand gram-negativer Bakterien spielen eine ursächliche Rolle in der Pathogenese der Sepsis. Eintrittspforte der Bakterien ist dabei häufig der Gastrointestinaltrakt, dessen...

    Dr. med Natascha C. Nüssler, G. Zhang… in Chirurgisches Forum ’96 fur experimentelle… (1996)

  9. No Access

    Chapter and Conference Paper

    Intestinale intraepitheliale Lymphozyten zeigen gesteigerte Proliferation und zytolytische Aktivität während akuter Graft-versus-Host Reaktion

    Zu den gefürchteten Komplikationen nach Knochenmarktransplantation zählt die Graft-versus-Host Reaktion (GvHR), die durch Zerstörung von Empfängergewebe durch immunkompetente T-Zellen des Spenders definiert is...

    R. A. Hoffman, N. C. Schattenfroh… in Chirurgisches Forum ’95 für experimentelle… (1995)

  10. No Access

    Chapter

    Electrodynamic Signatures of the Plasma Sheet Boundary Layer in the Evening Ionosphere

    We report on observations taken by DMSP-F9 and DE-2 while crossing the polar cap/auroral oval boundary in the evening sector. Season-dependent and latitudinally narrow regions of rapid, eastward plasma flows w...

    W. J. Burke, J. S. Machuzak, N. C. Maynard… in Physical Signatures of Magnetospheric Boun… (1994)

  11. No Access

    Chapter and Conference Paper

    Stickstoffmonoxyd-Produktion nach Dünndarmtransplantation der Ratte

    In der Dünndarmkonservierung nimmt Stickstoffmonoxyd (·N=O) offensichtlich eine zweideutige Rolle ein. Die durch das konstitutive Enzym regulierte ·N=O Produktion vermindert unter physiologischen und pathophys...

    Dr. A. R. Mueller, K. P. Platz, J. M. Langrehr, R. A. Hoffman… in Chirurgisches Forum ’94 (1994)

  12. No Access

    Article

    Untersuchungen über den Immunstatus bei langzeitüberlebenden Empfängern von allogenen Dünndarmtransplantaten im Rattenmodell

    Funktionelles Langzeitüberleben (über 400 Tage) von allogenen Dünndarmtransplantaten kann in bestimmten Rattenstrangkombinationen nach nur kurzfristiger initialer immunsuppressiver Therapie mit Cyclosporin A o...

    Dr. J. M. Langrehr, K. K. W. Lee, R. A. Hoffman, R. Lohmann… in Acta chirurgica Austriaca (1993)

  13. No Access

    Article

    Serumnitrit/-nitratverlauf bei akuter Abstoßung allogener Dünndarmtransplantate im Rattenmodell

    Grundlagen

    Dr. J. M. Langrehr, H. Keck, A. R. Müller, R. L. Simmons… in Acta Chirurgica Austriaca (1993)

  14. No Access

    Chapter

    Nitric Oxide Synthesis in Sponge Matrix Allografts Coincides with the Initiation of the Allogeneic Response

    The investigation of the biological effects of nitric oxide (∙N = O) has been of increasing interest in the recent past. Nitric oxide is a product of oxidative L-arginine metabolism, in which L-arginine is metabo...

    J. M. Langrehr, J. Stadler, T. R. Billiar… in Host Defense Dysfunction in Trauma, Shock … (1993)

  15. No Access

    Article

    Phase Transformations in Co/Nb and Co/Zr Multilayer Film Stacks.

    Ion-beam mixing and isothermal annealing techniques were applied to induce phase transformations in Co/Nb and Co/Zr multilayer film stacks. Transmission electron microscopy(TEM) and x-ray diffraction(XRD) were...

    J. C. Lin, R. A. Hoffman in MRS Online Proceedings Library (1992)

  16. No Access

    Article

    Interaction of harderian glands, illumination, and temperature on thyroid hormones in golden hamsters

    In this study, Harderianectomy (Hdx) has been shown to differentially modify circulating levels of the thyroid hormones, T4 and T3, in male and female golden hamsters exposed to low photic intensities or to moder...

    R. A. Hoffman, L. B. Johnson, M. K. Vaughan… in Journal of Comparative Physiology B (1989)

  17. No Access

    Article

    Photoluminescence, Raman Scattering and RBS/Channeling of Epitaxial Fluorides

    Growth conditions are described for producing high quality crystalline films of CaF2 on (100) and (111) GaAs and LaF3, CeF3 and NdF3 on (111) Si. Rutherford backscattering/channeling, low temperature (<2K) photol...

    W. J. Choyke, J. L. Bradshaw, A. Mascarenhas, Z. C. Feng… in MRS Online Proceedings Library (1985)

  18. No Access

    Article

    Observations of inverted-V electron precipitation

    The characteristics of inverted-V electron precipitation fluxes deduced predominantly from observations by the Atmosphere Explorer satellites are reviewed. The energy and pitch angle distributions are presente...

    C. S. Lin, R. A. Hoffman in Space Science Reviews (1982)

  19. No Access

    Chapter and Conference Paper

    Initial Observations of Magnetospheric Boundaries by Explorer 45 (S3)

    We present a review of initial results obtained from the NASA Small Scientific Satellite (Explorer 45) concerning the nature of three magnetospheric boundaries observed by the satellite near the equatorial pla...

    T. A. Fritz, P. H. Smith, D. J. Williams… in Correlated Interplanetary and Magnetospher… (1974)

  20. No Access

    Article

    Hypoxic inactivation of cold-induced brown fat thermogenesis

    Chez des rats adaptés au froid, non anesthésiés, placés brièvement dans une atmosphère de 12% d'oxygène, on observer un arrêt immédiat de la thermogénèse de la graisse brune. Cet effet semble s'expliquer par l...

    D. D. Schnakenberg, R. A. Hoffman in Experientia (1972)

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