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Article
Phase 1b study of lenalidomide in combination with rituximab-CHOP (R2-CHOP) in patients with B-cell lymphoma
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Chapter
Lymphome de Hodgkin : traitement de première ligne des stades avancés
Le paysage de la prise en charge des lymphomes de Hodgkin (LH) avancés s’est sensiblement modifié durant les 10 dernières années. L’introduction de nouveaux schémas thérapeutiques plus intenses permet d’amélio...
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Chapter
Maladie de Hodgkin
Le lymphome de Hodgkin (LH)reste une entité distincte au sein des lymphomes malins. C’ est une affection dont le diagnostic repose sur un critère uniquement morphologique: la présence de cellules de Sternberg ...
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Chapter
Lymphomes malins non hodgkiniens
Les lymphomes malins non hodgkiniens (LMNH)sont des proliférations malignes du tissu lym- phoïde dont le diagnostic résulte toujours de l’examen d’une biopsie tissulaire.Celle-ci permet de les distinguer du ly...
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Article
Immunological classification of acute myeloblastic leukemias: relevance to patient outcome
Immunophenoty** is a major tool to assign acute leukemia blast cells to the myeloid lineage. However, because of the large heterogeneity of myeloid-related lineages, no clinically relevant immunological clas...
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Article
Sequential chemotherapy by CHOP and DHAP regimens followed by high-dose therapy with stem cell transplantation induces a high rate of complete response and improves event-free survival in mantle cell lymphoma: a prospective study
Mantle cell lymphoma (MCL) is a distinct clinico-pathological entity with a poor prognosis. We have conducted a prospective study in patients with MCL to evaluate a therapeutic strategy in which CHOP polychemo...
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Article
Phase I study of cinchonine, a multidrug resistance reversing agent, combined with the CHVP regimen in relapsed and refractory lymphoproliferative syndromes
Overexpression of P-glycoprotein (P-gp) in cancer cells reduces intracellular accumulation of various anticancer drugs including anthracyclines and vinca alkaloids. This multidrug resistance (MDR) phenotype ca...