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  1. No Access

    Chapter

    Mutagenesis

    Bacterial plasmids are autonomously replicating mini chromosomes (replicons) which contain genetic information for many different properties, including the production of toxins and adhesion antigens, resistanc...

    R. Eichenlaub, A. Pühler, V. Krishnapillai, H. Heilmann in Advanced Molecular Genetics (1984)

  2. No Access

    Chapter

    Basic Methods

    Gene transfer in bacteria occurs by three main processes: transformation and transfection, which involve the direct uptake of free DNA by bacteria; transduction, which involves bacteriophage mediated transmiss...

    M. P. O’Connell, U. Priefer, N. Datta, M. E. Nugent in Advanced Molecular Genetics (1984)

  3. No Access

    Chapter

    Gene Cloning

    Genetic recombination is the fundamental biological process of exchange of genetic information between different chromosomes. Its constant activity during evolution has enabled the large number of spontaneousl...

    K. N. Timmis, G. Brady, J. Frey, A. Pühler, U. Priefer in Advanced Molecular Genetics (1984)

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    Chapter

    Bioluminescent REC A Mutants of Rhizobium as Model Organisms in Risk Assessment Studies

    A major concern about the deliberate release of genetically modified microorganisms (GEMMOs) is that the released organism exerts a potential disruptive effect on the biotic community of its target eco-system....

    W. Selbitschka, A. Pühler, R. Simon in The Release of Genetically Modified Microo… (1992)

  5. No Access

    Article

    Prenatal hypertrophic cardiomyopathy and pericardial effusion in carbohydrate-deficient glycoprotein syndrome

    M. T. García Silva, J. de Castro, H. Stibler in Journal of Inherited Metabolic Disease (1996)

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    Article

    Iodine species and the endocrine system: thyroid hormone levels in adult Danio rerio and develo** Xenopus laevis

    Recently a new approach for the analysis of iodinated organic species in human serum has been developed using liquid chromatography–inductively coupled plasma–mass spectrometry (LC–ICP–MS). This method enable...

    R. Simon, J. Tietge, B. Michalke, S. Degitz in Analytical and Bioanalytical Chemistry (2002)

  7. No Access

    Article

    Congenital disorder of glycosylation (CDG) type Ie. A new patient

    Summary: CDG Ie is caused by a deficiency of dolichol-phosphate-mannose synthase 1 (DPM1), an enzyme involved in N-glycan assembly in the endoplasmic reticulum. Three proteins are known t...

    M. T. García-Silva, G. Matthijs, E. Schollen in Journal of Inherited Metabolic Disease (2004)

  8. No Access

    Article

    Investigation of element distribution and homogeneity of TXRF samples using SR-micro-XRF to validate the use of an internal standard and improve external standard quantification

    Total reflection X-ray fluorescence analysis (TXRF) offers a nondestructive qualitative and quantitative analysis of trace elements. Due to its outstanding properties TXRF is widely used in the semiconductor i...

    C. Horntrich, S. Smolek, A. Maderitsch, R. Simon in Analytical and Bioanalytical Chemistry (2011)

  9. Article

    Open Access

    Progress of elemental anomalies of hippocampal formation in the pilocarpine model of temporal lobe epilepsy—an X-ray fluorescence microscopy study

    In the present paper, X-ray fluorescence microscopy was applied to follow the processes occurring in rat hippocampal formation during the post-seizure period. In the study, one of the status epilepticus animal mo...

    J. Chwiej, J. Kutorasinska, K. Janeczko in Analytical and Bioanalytical Chemistry (2012)

  10. Article

    Open Access

    Elemental changes in the hippocampal formation following two different formulas of ketogenic diet: an X-ray fluorescence microscopy study

    The main purpose of the following study was the determination of elemental changes occurring within hippocampal formation as a result of high-fat and carbohydrate-restricted ketogenic diet (KD). To realize it...

    J. Chwiej, A. Patulska, A. Skoczen in JBIC Journal of Biological Inorganic Chemi… (2015)