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  1. Article

    Open Access

    Elemental changes in the hippocampal formation following two different formulas of ketogenic diet: an X-ray fluorescence microscopy study

    The main purpose of the following study was the determination of elemental changes occurring within hippocampal formation as a result of high-fat and carbohydrate-restricted ketogenic diet (KD). To realize it...

    J. Chwiej, A. Patulska, A. Skoczen… in JBIC Journal of Biological Inorganic Chemi… (2015)

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  2. No Access

    Article

    Safe biotechnology. Part 6. Safety assessment, in respect of human health, of microorganisms used in biotechnology

    The assessment of microorganisms in respect to human health is an important step for the introduction of new natural and genetically modified production strains to biotechnology. This report outlines the poten...

    H. L. M. Lelieveld, H. Bachmayer, B. Boon… in Applied Microbiology and Biotechnology (1995)

  3. Article

    Safe biotechnology (5). Recommendations for safe work with animal and human cell cultures concerning potential human pathogens

    The benefits of using animal or human cell cultures have been clearly demonstrated in diagnostic and therapeutic research and in their application for manufacturing. Cell cultures serve as a tools for the prod...

    W. Frommer, L. Archer, B. Boon, G. Brunius… in Applied Microbiology and Biotechnology (1993)

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  4. No Access

    Article

    Safe biotechnology (4). Recommendations for safety levels for biotechnological operations with microorganisms that cause diseases in plants

    The Working Party on Safety in Biotechnology of the European Federation of Biotechnology has proposed a classification of microorganisms that cause diseases in plants. In this paper appropriate safety levels a...

    W. Frommer, L. Archer, B. Boon, G. Brunius… in Applied Microbiology and Biotechnology (1992)

  5. No Access

    Chapter

    Bioluminescent REC A Mutants of Rhizobium as Model Organisms in Risk Assessment Studies

    A major concern about the deliberate release of genetically modified microorganisms (GEMMOs) is that the released organism exerts a potential disruptive effect on the biotic community of its target eco-system....

    W. Selbitschka, A. Pühler, R. Simon in The Release of Genetically Modified Microo… (1992)

  6. No Access

    Chapter

    Squeezed States and Quadratic Hamiltonians: A Wigner Distribution Approach

    For some time now there has been much interest in a special class of quantum states of the radiation field known as squeezed coherent states or simply squeezed states1–5. In fact the first experimental observatio...

    R. Simon in Symmetries in Science II (1986)

  7. No Access

    Chapter

    Plasmid Interactions in Rhizobium; Incompatibility Between Symbiotic Plasmids

    Plasmid profiles were determined for twenty four strains of R. trifolii. All the strains harboured at least three plasmids and as many as eight were present in some strains. Southern hybridisation with cloned R. ...

    Michael O’Connell, D. Dowling, J. Neilan… in Advances in Nitrogen Fixation Research (1984)

  8. No Access

    Chapter

    Advances in the Genetics of Free-Living and Symbiotic Nitrogen Fixing Bacteria

    It is evident that the knowledge about biological nitrogen fixation was enormously increased when genetic systems in free-living and symbiotic nitrogen fixing bacteria were developed and used for the analysis ...

    Alfred Pühler, M. O. Aguilar, M. Hynes, P. Müller… in Advances in Nitrogen Fixation Research (1984)

  9. No Access

    Chapter

    Mutagenesis

    Bacterial plasmids are autonomously replicating mini chromosomes (replicons) which contain genetic information for many different properties, including the production of toxins and adhesion antigens, resistanc...

    R. Eichenlaub, A. Pühler, V. Krishnapillai, H. Heilmann… in Advanced Molecular Genetics (1984)

  10. No Access

    Chapter

    Basic Methods

    Gene transfer in bacteria occurs by three main processes: transformation and transfection, which involve the direct uptake of free DNA by bacteria; transduction, which involves bacteriophage mediated transmiss...

    M. P. O’Connell, U. Priefer, N. Datta, M. E. Nugent… in Advanced Molecular Genetics (1984)

  11. No Access

    Chapter

    Gene Cloning

    Genetic recombination is the fundamental biological process of exchange of genetic information between different chromosomes. Its constant activity during evolution has enabled the large number of spontaneousl...

    K. N. Timmis, G. Brady, J. Frey, A. Pühler, U. Priefer… in Advanced Molecular Genetics (1984)

  12. No Access

    Article

    A Broad Host Range Mobilization System for In Vivo Genetic Engineering: Transposon Mutagenesis in Gram Negative Bacteria

    We have developed a new vector strategy for the insertion of foreign genes into the genomes of gram negative bacteria not closely related to Escherichia coli. The system consists of two components: special E. col...

    R. Simon, U. Priefer, A. Pühler in Bio/Technology (1983)

  13. No Access

    Article

    Der Samenansatz bei Oenotheren-Kreuzungen

    10Oenotheren-Arten aus der SektionRaimannia wurden mit derOe. Hookeri reziprok gekreuzt. Die Kreuzungen setzten recht verschieden an. Um sie untereinander vergleichen zu können, wurde berechnet, wieviel von den f...

    Prof. Dr. J. Schwemmle, R. Simon in Planta (1956)