8 Result(s)
within
R Schoental
Science, Humanities and Social Sciences, multidisciplinary
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Article
Carcinogens in Chinese Incense Smoke
CONSIDERATION of the high incidence of naso-pharyngeal cancer among the Chinese1 led us to search for carcinogenic constituents in condensates from burning Chinese incense. Using thin-layer arid column chromatogr...
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Article
Effects of N-Methyl-N-nitrosourethane on Cells in Tissue Culture
A COMMUNICATION on the morphological conversion of cells in vitro by N-nitrosomethylurea by Sanders and Burford1 prompts me to report similar experiments performed about 5 years ago in which the related and very ...
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Article
Induction of Intestinal Tumours by N-Ethyl-N-nitrosourethane
INTESTINAL tumours, though very rare in laboratory rodents, have been induced by several types of carcinogenic agents, including polycyclic aromatic hydrocarbons, 4-dimethylaminostilbene, 2-acetyl-aminofluoren...
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Article
Induction of Tumours of the Stomach in Rats and Mice by N-nitroso-N-alkylurethanes
THE induction of squamous carcinoma of the stomach and, of the oesophagus in the rat by N-nitroso-N-methyl-urethane (NMU)1 and by some other nitrosamines2 has been reported. Squamous tumours of the stomach have b...
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Article
Photodecomposition of N-alkyl-N-nitroso-urethanes
IN the course of investigations of the carcinogenic action of N-methyl-N-nitroso-urethane (NMU)1 it was observed that dilute solutions of this compound in aqueous ethanol, when left in direct sunshine, became dec...
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Article
Interaction of the Carcinogenic N-Methyl-Nitrosourethane with Sulphydryl Groups
IN a preliminary communication I recently reported the production of lung adenoma in mice and squamous lung carcinoma in a rat, which was exposed to gaseous diazomethane. Among other rats given N-methyl-N-nitroso...
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Article
Isolation of 3 : 4-9 : 10-Dibenzopyrene from Coal-Tar
BY fractionation of coal-tar on alumina, Berenblum and Schoental1 demonstrated that the fraction preceding and that following the one containing 3 : 4-benzpyrene were carcinogenic to rodents though free from spec...
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Article
Palatability of N-Oxides of Pyrrolizidine Alkaloids as a Factor in Senecio Poisoning
RECENT chemical studies revealed that pyrrolizidine alkaloids are accompanied in the plants by their N-oxides1. In young growing plants, N-oxides may constitute more than 90 per cent of the alkaloid content, whil...
