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  1. Article

    Open Access

    Target gene selectivity of hypoxia-inducible factor-α in renal cancer cells is conveyed by post-DNA-binding mechanisms

    Inactivation of the von Hippel–Lindau tumour suppressor in renal cell carcinoma (RCC) leads to failure of proteolytic regulation of the α subunits of hypoxia-inducible factor (HIF), constitutive upregulation o...

    K W Lau, Y-M Tian, R R Raval, P J Ratcliffe, C W Pugh in British Journal of Cancer (2007)

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  2. No Access

    Article

    Identification of novel VHL targets that are associated with the development of renal cell carcinoma

    von Hippel–Lindau (VHL) disease is a dominantly inherited family cancer syndrome characterized by the development of retinal and central nervous system haemangioblastomas, renal cell carcinoma (RCC) and phaeoc...

    M Abdulrahman, E N Maina, M R Morris, M Zatyka, R R Raval, R E Banks… in Oncogene (2007)