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  1. No Access

    Article

    Improved antibiotic-free plasmid vector design by incorporation of transient expression enhancers

    Methods to improve plasmid-mediated transgene expression are needed for gene medicine and gene vaccination applications. To maintain a low risk of insertional mutagenesis-mediated gene activation, expression-a...

    J M Luke, J M Vincent, S X Du, U Gerdemann, A M Leen, R G Whalen… in Gene Therapy (2011)

  2. No Access

    Chapter and Conference Paper

    DNA Vaccines for Infectious Diseases, Allergies and Cancer

    DNA vaccination involves the direct injection of a suitable designed plasmid DNA molecule into a tissue such that the antigenic proteins encoded by the plasmid are expressed in the cells of the treated host. T...

    R. G. Whalen in Symposium in Immunology VII (1998)

  3. No Access

    Chapter

    Cellular Systems and Aspects of Protein Synthesis in the Study of Muscle Cell Differentiation

    Among those systems that molecular biologists have chosen to study terminal differentiation, the genesis of skeletal muscle cells provides many of the advantages required to facilitate experimentation. Mononuc...

    R. G. Whalen in Gene Expression in Normal and Transformed Cells (1983)