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Article
Drosophila melanogaster as a model for studying protein-encoding genes that are resident in constitutive heterochromatin
The organization of chromosomes into euchromatin and heterochromatin is one of the most enigmatic aspects of genome evolution. For a long time, heterochromatin was considered to be a genomic wasteland, incompa...
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Article
FB elements can promote exon shuffling: a promoter-less white allele can be reactivated by FB mediated transposition in Drosophila melanogaster
Foldback (FB) elements are transposable elements found in many eukaryotic genomes; they are thought to contribute significantly to genome plasticity. In Drosophila melanogaster, FBs have been shown to be involved...
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Article
MAX, a novel retrotransposon of the BEL-Pao family, is nested within the Bari 1 cluster at the heterochromatic h39 region of chromosome 2 in Drosophila melanogaster
A homogeneous array of 80 tandem repeats of the Bari1 transposon is located in the pericentromeric h39 region of chromosome 2 of Drosophila melanogaster. Here, we report that the Bari1 cluster is interrupted by a...
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Article
dtctex-1, the Drosophila melanogaster homolog of a putative murine t-complex distorter encoding a dynein light chain, is required for production of functional sperm
Tctex-1 is a light chain of the cytoplasmic and flagellar dyneins and a candidate for one of the distorter products that cause transmission ratio distortion in mice. We report the identification, characteriza...
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Article
The Drosophila melanogaster gene for the NADH:ubiquinone oxidoreductase acyl carrier protein: developmental expression analysis and evidence for alternatively spliced forms
We have isolated the Drosophila melanogaster gene encoding the mitochondrial acyl carrier protein (mtACP), a subunit of NADH:ubiquinone oxidoreductase involved in de novo fatty acid synthesis in the mitochondrio...
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Article
Identification of nuclear genes encoding mitochondrial proteins: isolation of a collection of D. melanogaster cDNAs homologous to sequences in the Human Gene Index database
As a first step towards using cross-species comparison to complete the inventory of the nuclear genes that encode mitochondrial polypeptides, and ultimately to understand their function through systematic mol...
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Article
The S-adenosyl-l-homocysteine hydrolase of Drosophila melanogaster : identification, deduced amino acid sequence and cytological localization of the structural gene
S-adenosyl-l-homocysteine hydrolase (AdoHcyase, EC 3.3.1.1) catalyzes the hydrolysis of S-adenosyl-l-homocysteine to adenosine and homocysteine and thus plays a crucial role in normal cellular metabolism. We hav...
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Article
The distribution of the transposable elementBari-1 in theDrosophila melanogaster andDrosophila simulans genomes
The distribution of the transposable elementBari-1 inD. melanogaster andD. simulans was examined by Southern blot analysis and byin situ hybridization in a large number of strains of different geographical origin...
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Article
A method for the molecular characterization of bb l loci in Drosophila melanogaster
In this work we have used a method that allows a rapid and precise quantification of rRNA genes. With the purpose of examining small numbers of rRNA genes, we used Drosophila melanogaster embryos which are inviab...