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Chapter and Conference Paper
Down-Regulation of DHRS1 Predicts Poor Survival Outcome of Patients with Hepatocellular Carcinoma
Hepatocellular carcinoma (HCC) is one of the leading causes of cancer-related deaths worldwide, with complicated stages. The HCC patients almost never show clinical signs or symptoms until the cancer is in its...
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Article
Open AccessMelatonin and doxorubicin synergistically enhance apoptosis via autophagy-dependent reduction of AMPKα1 transcription in human breast cancer cells
Doxorubicin is one of the most effective agents used to treat various cancers, including breast cancer, but its usage is limited by the risk of adverse effects, including cardiotoxicity. Melatonin, a natural h...
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Article
Open AccessMelatonin prevents doxorubicin-induced cardiotoxicity through suppression of AMPKα2-dependent mitochondrial damage
The clinical application of doxorubicin, one of the most effective anticancer drugs, has been limited due to its adverse effects, including cardiotoxicity. One of the hallmarks of doxorubicin-induced cytotoxic...
