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  1. Article

    Open Access

    Experimental study of PLLA/INH slow release implant fabricated by three dimensional printing technique and drug release characteristics in vitro

    Local slow release implant provided long term and stable drug release in the lesion. The objective of this study was to fabricate biodegradable slow release INH/PLLA tablet via 3 dimensional printing technique...

    Gui Wu, Weigang Wu, Qixin Zheng, **gfeng Li, Jianbo Zhou… in BioMedical Engineering OnLine (2014)

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  2. Article

    Open Access

    Different responses to mechanical injury in neonatal and adult ovine articular cartilage

    Articular cartilage injury remains a major challenge in orthopedic surgery. This study aimed to identify differences in gene expression and molecular responses between neonatal and adult articular cartilage du...

    Xuhong Xue, Qixin Zheng, Hongbin Wu, Lixue Zou, Peng Li in BioMedical Engineering OnLine (2013)

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  3. No Access

    Article

    Anterior surgical options for the treatment of cervical spondylotic myelopathy in a long-term follow-up study

    To provide a basis for the choice of anterior surgery procedures in the treatment of cervical spondylotic myelopathy (CSM) through long-term follow-up.

    **gfeng Li, Qixin Zheng, **aodong Guo… in Archives of Orthopaedic and Trauma Surgery (2013)

  4. No Access

    Article

    Angiogenesis induced by IKVAV-Containing amphiphile peptide in vivo

    An IKVAV (Isoleucine-Lysine-Valine-Alanine-Valine)-containing peptide amphiphile molecule (IKVAV-PA) was implanted subcutaneouly into rat backbone in the middle. Angiogenesis induced by IKVAV-PA was evaluated in ...

    Yulin Song 宋玉林, Yixiu Li, Qixin Zheng in Journal of Wuhan University of Technology-… (2010)

  5. No Access

    Article

    Cytocompatibility of self-assembled hydrogel from IKVAV-containing peptide amphiphile with neural stem cells

    Neural Stem Cells (NSCs) were incubated with self-assembled hydrogel from IKVAV-containing peptide amphiphile (IKVAV-PA) for one week. The cytocompatibility of hydrogel was evaluated. NSCs were seeded in three...

    Yulin Song 宋玉林, Qixin Zheng, **aodong Guo… in Journal of Wuhan University of Technology-… (2009)

  6. No Access

    Article

    Two-dimensional effects of hydrogel self-organized from IKVAV-containing peptides on growth and differentiation of NSCs

    The neural stem cells (NSCs) were seeded in the surface layer of hydrogels made of IKVAV-containing peptide amphiphile. Two-dimensional effects of hydrogel on growth and differentiation of NSCs were investigat...

    Yulin Song 宋玉林, Qixin Zheng, Yongchao Wu… in Journal of Wuhan University of Technology-… (2009)

  7. No Access

    Article

    Expression of MMP-1 in cartilage and synovium of experimentally induced rabbit ACLT traumatic osteoarthritis: immunohistochemical study

    To observe the level and the distribution of MMP-1 in cartilage and synovium over the progression of OA in rabbit ACLT model, and to explore the relationship between the amount of MMP-1 expression and the degr...

    Hongbin Wu, **gyuan Du, Qixin Zheng in Rheumatology International (2008)

  8. No Access

    Article

    Ectopic bone formation in vivo induced by a novel synthetic peptide derived from BMP-2 using porous collagen scaffolds

    To investigate the osteoinductive and ectopicly osteogenic effects of a novel peptide P24 derived from bone morphogenetic protein 2 (BMP2), biodegradable collagen scaffolds (CS) were used to load BMP-2-derived...

    Quan Yuan, Hongwei Lu, Shuo Tang, Kai Liu… in Journal of Wuhan University of Technology-… (2007)

  9. No Access

    Article

    Biocompatibility of tri-block bone-matrix material in vitro

    To evaluate the biocompatibility of poly(lactic acid/glycolic acid/ asparagic acid-co-polyethylene glycol)(PLGA-[ASP-PEG]) tri-block copolymer in vitro, L929 fibroblast was co-cultured with the copolymer for c...

    Deyu Duan Ph D 段德宇, Qixin Zheng, Jie Hao… in Journal of Wuhan University of Technology-… (2007)