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Article
Open AccessNeonatal GABAergic transmission primes vestibular gating of output for adult spatial navigation
GABAergic interneurons are poised with the capacity to shape circuit output via inhibitory gating. How early in the development of medial vestibular nucleus (MVN) are GABAergic neurons recruited for feedforwar...
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Article
Open AccessThe secondary somatosensory cortex gates mechanical and heat sensitivity
The cerebral cortex is vital for the processing and perception of sensory stimuli. In the somatosensory axis, information is received primarily by two distinct regions, the primary (S1) and secondary (S2) soma...
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Article
Molten salts synthesis of Li1.1Mn0.55Ni0.3Co0.05O2 oxide cathode material for lithium-ion batteries
Li1.1Mn0.55Ni0.3Co0.05O2 (LMRO) oxides were prepared by a hydrothermal method and the molten salts-assisted sintering method. When the mass ratio of urea and the metal salts is 0.025, the material (0.025NS-LMRO) ...
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Article
Study of Optimal and Joint Allocations of Water and land Resources for Multiple Objectives
A mismatch of water and land resources leads to various water problems and degradation of the ecological function of a basin. Existing water resource allocations and land resource allocations consist of differ...
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Article
Open AccessRational design of a sensitivity-enhanced tracer for discovering efficient APC–Asef inhibitors
The adenomatous polyposis coli (APC)–Rho guanine nucleotide exchange factor 4 (Asef) protein–protein interaction (PPI) is essential for colorectal cancer metastasis, making it a promising drug target. Herein, ...
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Article
Plasminogen activator inhibitor-1 gene promoter 4G/5G polymorphism and risks of peripherally inserted central catheter–related venous thrombosis in patients with lung cancer: a prospective cohort study
This study investigated the influence of plasminogen activator inhibitor-1 (PAI-1) gene polymorphisms and other contributing clinical factors on peripherally inserted central catheter–related venous thrombosis...
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Article
A wax gourd flesh-derived porous carbon activated by different activating agents as lithium ion battery anode material
A wax gourd flesh-derived porous carbon material has been prepared using different activating agents through the pyrolysis carbonization method. The materials activated by CaCl2 and KOH were marked as WGF-CaCl2 a...
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Article
Assessing the thrombosis risk of peripherally inserted central catheters in cancer patients using Caprini risk assessment model: a prospective cohort study
There was no optimal risk assessment tool to stratify the risk of peripherally inserted central catheter-related venous thromboembolism (PICC-RVT) in cancer patients. We currently use the Caprini risk assessme...
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Article
SiO2 aerogel @ carbon nanotube anchored on graphene sheet as anode material for lithium ion battery
SiO2 aerogel @ carbon nanotube anchored on graphene sheet (SiO2/CNT/GE) has been produced by a mechanical mixing method. The SiO2 nanoparticle and carbon nanotube are dispersed on graphene sheet. When the current...
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Article
Reply to: Binding site for MDL-801 on SIRT6
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Article
A waste corn cob core-derived SiO2 @ graphene-like carbon nanocomposite and its application in lithium-ion battery
A waste corn cob core-derived SiO2 @ graphene-like carbon nanocomposite (CCC) has been synthesized by a hydro-thermal and high-temperature carbonization process. The CCC material is carbonized at 900 °C (CCC-900)...
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Article
Synthesis of porous carbon materials derived from waste buttonwoods, pineapple peels, and lettuce leaves and comparison of the electrochemical performances for lithium-ion battery
The waste buttonwoods, pineapple peels, and lettuce leaves have been activated by KOH and carbonized through a high-temperature process. When used as the anode materials for lithium-ion battery, the activated ...
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Article
Fabrication of SiO2 aerogel supported C/TiO2 nanocomposite and Li+ storage performance
SiO2 aerogel supported C/TiO2 (SiO2@C/TiO2) nanocomposite was compounded via a simple polymerizing and sintering methods. TiO2 and carbon sphere are closely interlinked with the SiO2 aerogel of the network struct...
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Article
Identification of a cellularly active SIRT6 allosteric activator
SIRT6, a member of the SIRT deacetylase family, is responsible for deacetylation of histone H3 Nε-acetyl-lysines 9 (H3K9ac) and 56 (H3K56ac). As a tumor suppressor, SIRT6 has frequently been found to have low exp...
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Article
Peptidomimetic inhibitors of APC–Asef interaction block colorectal cancer migration
Adenomatous polyposis coli (APC) is shown to promote colorectal cancer cell migration by activating the guanine nucleotide exchange factor Asef. Structure-based design resulted in the development of peptidomim...
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Article
Open AccessReversible lysine acetylation is involved in DNA replication initiation by regulating activities of initiator DnaA in Escherichia coli
The regulation of chromosomal replication is critical and the activation of DnaA by ATP binding is a key step in replication initiation. However, it remains unclear whether and how the process of ATP-binding t...
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Article
Open AccessMutual modulation between norepinephrine and nitric oxide in haemocytes during the mollusc immune response
Nitric oxide (NO) is one of the most important immune molecules in innate immunity of invertebrates and it can be regulated by norepinephrine in ascidian haemocytes. In the present study, the mutual modulation...
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Article
The study on the Li-storage performances of bamboo charcoal (BC) and BC/Li2SnO3 composites
Bamboo charcoal/Li2SnO3 composites for lithium-ion batteries were synthesized by a sol–gel route. The structure, morphology, and electrochemical properties of the composites were detected by means of X-ray diffra...
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Article
Graphene supported Li2SnO3 as anode material for lithium-ion batteries
The graphene supported Li2SnO3 composites were prepared via a deoxidation technique. The structure, morphology and electrochemical properties of the composites were detected by means of XRD, SEM, TEM, Raman, TGA ...
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Article
Preparation of graphene/BaFe12O19–Ni0.8Zn0.2Fe2O4 nanocomposite and its microwave absorbing properties
BaFe12O19–Ni0.8Zn0.2Fe2O4/graphene nanocomposites were prepared by a deoxidation technique. The structure, morphology and electromagnetic properties of the samples were detected by means of X-ray diffraction, sca...
