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Article
Open AccessExosome microRNA-22 inhibiting proliferation, migration and invasion through regulating Twist1/CADM1 axis in osteosarcoma
This study aims to the function of miR-22 original mesenchymal stem cells (MSC) on osteosarcoma (OS) proliferation, migration and invasion. Bio-informatics analysis including GEO2R analysis, Gene Ontology anal...
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Article
Open AccessPotential application of hydrogel to the diagnosis and treatment of multiple sclerosis
Multiple sclerosis (MS) is a chronic demyelinating disease of the central nervous system. This disorder may cause progressive and permanent impairment, placing significant physical and psychological strain on ...
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Article
N6-methyladenine DNA Demethylase ALKBH1 Regulates Mammalian Axon Regeneration
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Article
Platelet-Activating Factor Deteriorates Lysophosphatidylcholine-Induced Demyelination Via Its Receptor-Dependent and -Independent Effects
Accumulating evidence suggests that platelet-activating factor (PAF) increases the inflammatory response in demyelinating diseases such as multiple sclerosis. However, PAF receptor (PAFR) antagonists do not sh...
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Article
Current Understanding of Platelet-Activating Factor Signaling in Central Nervous System Diseases
Platelet-activating factor (PAF) is a bioactive lipid mediator which serves as a reciprocal messenger between the immune and nervous systems. PAF, a pluripotent inflammatory mediator, is extensively expressed ...
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Article
A model of acute central cervical spinal cord injury syndrome combined with chronic injury in goats
To develop a large animal model for acute central cervical spinal cord injury syndrome (ACCSCIS.
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Article
Attenuated Reactive Gliosis and Enhanced Functional Recovery Following Spinal Cord Injury in Null Mutant Mice of Platelet-Activating Factor Receptor
Platelet-activating factor (PAF) is a unique phosphoglycerine that mediates the biological functions of both immune and nervous systems. Excessive PAF plays an important role in neural injury via its specific ...
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Article
Cervical pedicle screw fixation at C6 and C7
Background: Cervical pedicle screw fixation is an effective method for treating traumatic and non traumatic injuries. But many studies have reported higher incidence of cervical pedicle penetration, so many resea...
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Article
Reciprocal Modulation Between Microglia and Astrocyte in Reactive Gliosis Following the CNS Injury
Reactive gliosis, also known as glial scar formation, is an inflammatory response characterized by the proliferation of microglia and astrocytes as well as astrocytic hypertrophy following injury in the centra...
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Article
An anatomic study on the placement of the second sacral screw and its clinical applications
The fixation of lumbosacral and sacral pelvis can be performed on the ilium and the Second Sacrum Vertebrae (S2). Although several studies on the anatomical and biomechanical features of S2 screw fixation have...
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Article
In Vivo Corrosion Resistance of Ca-P Coating on AZ60 Magnesium Alloy
Magnesium-based alloys are frequently reported as potential biodegradable orthopedic implant materials. Controlling the degradation rate and mechanical integrity of magnesium alloys in the physiological enviro...
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Article
Animal modelling of lumbar corpectomy and fusion and in vivo growth of spine supporting bone by titanium cage implants: An experimental study
In this study a lumbar spinal fusion animal model is established to assess the effect of spinal fusion cage, and explore the minimum area ratio of titanium cage section to vertebral section that ensures bone h...
