Skip to main content

and
  1. No Access

    Article

    Protecting mitochondria via inhibiting VDAC1 oligomerization alleviates ferroptosis in acetaminophen-induced acute liver injury

    Acetaminophen (APAP) overdose is a common cause of drug-induced liver injury (DILI). Ferroptosis has been recently implicated in APAP-induced liver injury (AILI). However, the functional role and underlying me...

    Baolin Niu, **aohong Lei, Qingling Xu, Yi Ju, Dongke Xu in Cell Biology and Toxicology (2022)

  2. No Access

    Article

    GADD45α alleviates acetaminophen-induced hepatotoxicity by promoting AMPK activation

    As an analgesic and antipyretic drug, acetaminophen (APAP) is commonly used and known to be safe at therapeutic doses. In many countries, the overuse of APAP provokes acute liver injury and even liver failure....

    Chunmin Li, Yanan Ming, Zhengyang Wang, Qingling Xu in Cellular and Molecular Life Sciences (2019)