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  1. Article

    Open Access

    Remodelling of tumour microenvironment by microwave ablation potentiates immunotherapy of AXL-specific CAR T cells against non-small cell lung cancer

    The complex immunosuppressive tumour microenvironment (TME) and lack of tumour-specific targets hinder the application of chimeric antigen receptor (CAR) T cells in the treatment of solid tumours. Combining lo...

    Bihui Cao, Manting Liu, Lu Wang, Kangshun Zhu, Mingyue Cai in Nature Communications (2022)

  2. Article

    Open Access

    IL-7 and CCL19-secreting CAR-T cell therapy for tumors with positive glypican-3 or mesothelin

    Although chimeric antigen receptor (CAR)-engineered T cells have shown great success in the treatment of B cell malignancies, this strategy has limited efficacy in patients with solid tumors. In mouse CAR-T ce...

    Nengzhi Pang, **gxuan Shi, Le Qin, Aiming Chen in Journal of Hematology & Oncology (2021)

  3. Article

    Open Access

    Feasibility and safety of fine positioning needle-mediated breathing control in CT-guided percutaneous puncture of small lung/liver nodules adjacent to diaphragm

    To assess the efficacy, safety, and feasibility of a separate inserted positioning fine needle-mediated breathing-control technique applied to computed tomography (CT)-guided percutaneous puncture for biopsy o...

    Qingde Wu, Bihui Cao, Yu** Zheng, Baoxia Liang, Manting Liu, Lu Wang in Scientific Reports (2021)