315 Result(s)
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Article
Clinical characteristics of 42 SARS patients and their treatment of integrative Chinese and western medicine
Objective: To understand the clinical manifestation of severe acute respiratory syndrome (SARS) and explore its effective treatment with integrative Chinese and western medicine (ICWM).Methods: The data of patie...
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Effects of integrative Chinese and Western medicine on arterial oxygen saturation in patients with severe acute respiratory syndrome
Objective: To evaluate the effects of treatment of integrative Chinese and Western medicine (ICWM) on arterial oxygen saturation (SaO2) in patients with severe acute respiratory syndrome (SARS).M...
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Supersensitivity to Amphetamine in Protein Kinase-C Interacting Protein/HINT1 Knockout Mice
Protein kinase C interacting protein/histidine triad nucleotide binding protein 1 (PKCI/HINT1) is a member of the histidine triad protein family. Although this protein is widely expressed in the mammalian brai...
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Open AccessIdentification of MSRA gene on chromosome 8p as a candidate metastasis suppressor for human hepatitis B virus-positive hepatocellular carcinoma
The prognosis of patients with hepatocellular carcinoma (HCC) still remains very dismal, which is mainly due to metastasis. In our previous studies, we found that chromosome 8p deletions might contribute to me...
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Open AccessFamilial aggregation analysis of gene expressions
Traditional studies of familial aggregation are aimed at defining the genetic (and non-genetic) causes of a disease from physiological or clinical traits. However, there has been little attempt to use genome-w...
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Open AccessGlioma stem cells are more aggressive in recurrent tumors with malignant progression than in the primary tumor, and both can be maintained long-term in vitro
Despite the advances made during decades of research, the mechanisms by which glioma is initiated and established remain elusive. The discovery of glioma stem cells (GSCs) may help to elucidate the processes o...
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Open AccessGJB2 mutation spectrum in 2063 Chinese patients with nonsyndromic hearing impairment
Mutations in GJB2 are the most common molecular defects responsible for autosomal recessive nonsyndromic hearing impairment (NSHI). The mutation spectra of this gene vary among different ethnic groups.
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Improvement of awareness, treatment and control of hypertension among chronic kidney disease patients in China from 1999 to 2005
Controlling hypertension is important to protect renal function and prevent cardiovascular disease in chronic kidney disease (CKD) patients. However, data on hypertension awareness, treatment and control among...
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Open AccessBehavioural development of school-aged children who live around a multi-metal sulphide mine in Guangdong province, China: a cross-sectional study
The deleterious biological effects of low-level, long-term exposure to heavy metals are well known, and children are the most susceptible population. Dabaoshan Mine in the southeast of Guangdong Province is at...
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Open AccessMicroarray analysis of DNA damage repair gene expression profiles in cervical cancer cells radioresistant to 252Cf neutron and X-rays
The aim of the study was to obtain stable radioresistant sub-lines from the human cervical cancer cell line HeLa by prolonged exposure to 252Cf neutron and X-rays. Radioresistance mechanisms were investigated in ...
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Open AccessPrevalence of the metabolic syndrome in Pudong New Area of Shanghai using three proposed definitions among Chinese adults
The prevalence of metabolic syndrome (MS) has been increasing in China in recent years. The aim of this study is to estimate and compare the prevalence of MS among Chinese adults in Shanghai, one of the most e...
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Open AccessMicroRNA-221 and microRNA-222 regulate gastric carcinoma cell proliferation and radioresistance by targeting PTEN
MicroRNAs (miRNAs) can function as either oncogenes or tumor suppressor genes via regulation of cell proliferation and/or apoptosis. MiR-221 and miR-222 were discovered to induce cell growth and cell cycle pro...
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Open AccessPrognostic relevance of Bmi-1 expression and autoantibodies in esophageal squamous cell carcinoma
Overexpression of Bmi-1 has been observed in a variety of cancers, and it has been suggested to be an independent prognostic marker for the patients. The objective of this study was to determine the level of B...
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Deficiency in Endocannabinoid Signaling in the Nucleus Accumbens Induced by Chronic Unpredictable Stress
The nucleus accumbens (NAc) is a critical component of the reward circuitry, and dysfunction of the NAc may account for anhedonia and other symptoms of depression. Here, we investigated whether alterations in ...
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Open AccessChronic occupational exposure to hexavalent chromium causes DNA damage in electroplating workers
Occupational exposure to chromium compounds may result in adverse health effects. This study aims to investigate whether low-level hexavalent chromium (Cr(VI)) exposure can cause DNA damage in electroplating w...
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Open AccessSentinel lymph node biopsy as guidance for radical trachelectomy in young patients with early stage cervical cancer
The purpose of this study was to assess the feasibility and accuracy of sentinel lymph nodes (SLNs) detection using 99mTc phytate in predicting pelvic lymph nodes status for radical abdominal trachelectomy (RA...
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Open AccessZinc finger protein ZBTB20 expression is increased in hepatocellular carcinoma and associated with poor prognosis
Our previous studies showed that ZBTB20, a new BTB/POZ-domain gene, could negatively regulate α feto-protein and other liver-specific genes, concerning such as bio-transformation, glucose metabolism and the re...
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Open AccessEffective components screening and anti-myocardial infarction mechanism study of the Chinese medicine NSLF6 based on "system to system" mode
Shuanglong formula (SLF), a Chinese medicine composed of panax ginseng and salvia miltiorrhiza exhibited significant effect in the treatment of myocardial infarction (MI) in clinical. Because of the complex natur...
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Open AccessImpact of genital warts on health related quality of life in men and women in mainland China: a multicenter hospital-based cross-sectional study
Information on the health-related quality of life (HRQoL) of patients with genital warts (GW) in populations in mainland China is still limited. The aim of the study was to use a generic instrument to measure ...
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Open AccessComparison of five methods for genomic breeding value estimation for the common dataset of the 15th QTL-MAS Workshop
Genomic breeding value estimation is the key step in genomic selection. Among many approaches, BLUP methods and Bayesian methods are most commonly used for estimating genomic breeding values. Here, we applied ...
