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  1. No Access

    Article

    Proliferation and Apoptosis of Peripheral Blood Mononuclear Cells in Patients with Oral Lichen Planus

    Oral lichen planus (OLP) is generally accepted to be a T cell-mediated chronic inflammatory disease with an unclear pathogenesis. There have been numerous studies on the proliferation and apoptosis of T cells in ...

    **g Shan, Jiang-Min Ma, Ran Wang, Qing-Lan Liu, Yuan Fan in Inflammation (2013)

  2. No Access

    Article

    Silencing of miR155 Promotes the Production of Inflammatory Mediators in Guillain–Barré Syndrome In Vitro

    MicroRNA-155 (miR155) has been demonstrated as a central regulator of immune responses induced by inflammatory mediators. Previous studies suggest that miR155 may play adverse effects in various diseases. We h...

    Yu-Zhong Wang, Xun-Gang Feng, Qi-Guang Shi, Yan-Lei Hao, Yan Yang… in Inflammation (2013)

  3. No Access

    Article

    Interleukin-7 Receptor Single Nucleotide Polymorphism rs6897932 (C/T) and the Susceptibility to Systemic Lupus Erythematosus

    Emerging evidences were accumulated to support the view that aberrant interleukin-7 (IL-7) signaling might be associated with autoimmunity. Former studies demonstrated the single nucleotide polymorphism (SNP) ...

    **ao-Song Wang, Peng-Fei Wen, Min Zhang, Lin-Feng Hu, **g Ni, Li-Juan Qiu… in Inflammation (2014)

  4. No Access

    Article

    The Second-Generation mTOR Kinase Inhibitor INK128 Exhibits Anti-inflammatory Activity in Lipopolysaccharide-Activated RAW 264.7 Cells

    Cross-talk between the mTOR (mechanistic target of rapamycin) and NF-κB (nuclear factor kappa-B) pathways has been reported to regulate macrophage responses to lipopolysaccharide (LPS). In this study, we aimed...

    Hao Pan, Li-Hui Xu, Dong-Yun Ouyang, Yao Wang, Qing-Bin Zha, **ao-Feng Hou… in Inflammation (2014)

  5. No Access

    Article

    Angiotensin II-Derived Reactive Oxygen Species Promote Angiogenesis in Human Late Endothelial Progenitor Cells Through Heme Oxygenase-1 via ERK1/2 and AKT/PI3K Pathways

    Angiotensin II (Ang II), the main component of renin-angiotensin system, could mediate pathogenic angiogenesis in cardiovascular disorders. Late endothelial progenitor cells (EPCs) possess potent self-renewal ...

    **gting Mai, Qiong Qiu, Yong Qing Lin, Nian Sang Luo, Hai Feng Zhang… in Inflammation (2014)

  6. No Access

    Article

    Emerging Role of SIGIRR rs7396562(T/G) Polymorphism in Systemic Lupus Erythematosus in a Chinese Population

    Systemic lupus erythematosus (SLE) is a systemic autoimmune disease, with heterogeneous presentation. The aim of this study was to examine the association of a single-nucleotide polymorphism, rs7396562, of the...

    Yan Zhu, De-Guang Wang, **ao-Ke Yang, Sha-Sha Tao, Qing Huang, Hai-Feng Pan… in Inflammation (2014)

  7. No Access

    Article

    Systemic and Flap Inflammatory Response Associates with Thrombosis in Flap Venous Crisis

    Venous crisis represents the most common complication in flap surgery and often results in flap failure. The gold standard for free flap monitoring is frequent clinical examination. The current study examined ...

    Wei Du, Pan-Feng Wu, Li-Ming Qing, Cong-Yang Wang, Jie-Yu Liang, Fang Yu… in Inflammation (2015)

  8. No Access

    Article

    Antibodies to Type IV Collagen Induce Type 1 Autoimmune Pancreatitis

    Type 1 autoimmune pancreatitis (AIP) is prototypic autoantibody-mediated diseases. Sclerosis accompanied by fiber deposition is generally regarded as the primary lesion in the development of obliterative vascu...

    Qi-cai Liu, Feng Dong, Jian-feng Pan, Ze-hao Zhuang, Feng Gao… in Inflammation (2016)

  9. No Access

    Article

    Andrographolide Benefits Rheumatoid Arthritis via Inhibiting MAPK Pathways

    Andrographolide (AD) is the main compound distributed in medicinal herb Andrographis paniculata and exhibits anti-inflammatory activity. AD has been used for the treatment of multiple inflammatory diseases. Howev...

    Zun-zhong Li, Ju-peng Tan, Li-li Wang, Qing-hua Li in Inflammation (2017)

  10. No Access

    Article

    Penehyclidine Hydrochloride Decreases Pulmonary Microvascular Endothelial Inflammatory Injury Through a Beta-Arrestin-1-Dependent Mechanism

    Penehyclidine hydrochloride (PHC), a type of hyoscyamus drug, has both antimuscarinic and antinicotinic activities and retains potent central and peripheral anticholinergic activities. Compared with other hyos...

    Fei Zheng, Fei **ao, Qing-Hong Yuan, Qiang-Sheng Liu, Zong-Ze Zhang… in Inflammation (2018)

  11. No Access

    Article

    Target of MCC950 in Inhibition of NLRP3 Inflammasome Activation: a Literature Review

    MCC950 has been proposed as a specific small molecule inhibitor that can selectively block NLRP3 inflammasome activation. However, the exact mechanism of its action is still ambiguous. Accumulating investigati...

    Danbin Wu, Yefei Chen, Yingxin Sun, Qing Gao, Huhu Li, Zhengfei Yang… in Inflammation (2020)

  12. No Access

    Article

    Phosphoproteomics and Proteomics Reveal Metabolism as a Key Node in LPS-Induced Acute Inflammation in RAW264.7

    To better understand the acute inflammatory mechanisms, the modulation, and to investigate the key node in predicting inflammatory diseases, high-sensitivity LC-MS/MS-based proteomics and phosphoproteomics app...

    Yu Luo, Qing Jiang, Zhengwen Zhu, Haseeb Sattar, Jiasi Wu, Wenge Huang… in Inflammation (2020)

  13. Article

    Interleukin-1β Protection Against Experimental Sepsis in Mice

    The inflammatory response involving interleukin-1β (IL-1β) has been thought to play an important role in the development of late-phase sepsis. However, in this study, we wanted to explore the possibility of us...

    Hai-lei Guo, Fu-dong Shi, Qi Zhou, Qing-yang Liu, Yue-xin Wang, Yang Song… in Inflammation (2021)

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  14. No Access

    Article

    Melatonin Alleviates Cardiac Dysfunction Via Increasing Sirt1-Mediated Beclin-1 Deacetylation and Autophagy During Sepsis

    Cardiac dysfunction is a major cause leading to multiple organ failure in sepsis. Beclin-1-dependent autophagy has been evidenced to exert protective effects on hearts in sepsis. However, the mechanisms on how...

    Qiang-Zhong Pi, **ao-Wen Wang, Zhao-Lei Jian, Dan Chen, Cheng Zhang… in Inflammation (2021)

  15. No Access

    Article

    The Effect of Porphyromonas gingivalis Lipopolysaccharide on the Pyroptosis of Gingival Fibroblasts

    Periodontitis is a chronic inflammatory disease induced by Porphyromonas gingivalis (P. gingivalis) and other pathogens. P. gingivalis release various virulence factors including lipopolysaccharide (LPS). However...

    Yu-Yang Li, Qing Cai, Bao-Sheng Li, Shu-Wei Qiao, Jia-Yang Jiang, Dan Wang… in Inflammation (2021)

  16. Article

    Open Access

    Adipose-Derived Mesenchymal Stem Cells-Derived Exosomes Carry MicroRNA-671 to Alleviate Myocardial Infarction Through Inactivating the TGFBR2/Smad2 Axis

    Mesenchymal stem cells (MSCs) and their derived extracellular vesicles have been reported as promising tools for the management of heart disease. The aim of this study was to explore the function of adipose-de...

    Xue Wang, Yuhai Zhu, Chengcheng Wu, Wennan Liu, Yujie He, Qing Yang in Inflammation (2021)

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  17. No Access

    Article

    Activation of C3 and C5 May Be Involved in the Inflammatory Progression of PCM and GM

    Plasma cell mastitis (PCM) and granulomatous mastitis (GM) are the most common inflammatory diseases constituting nonbacterial mastitis (NBM). However, the pathogenesis of NBM remains unclear. In this study, r...

    **ao-qiang Li, Hong-guang Sun, **ao-hong Wang, Hao-jie Zhang… in Inflammation (2022)

  18. No Access

    Article

    Expressions of Interleukin-27 in Oral Lichen Planus, Oral Leukoplakia, and Oral Squamous Cell Carcinoma

    The present study aimed to detect the expression of interleukin-27 (IL-27) in tissues of oral lichen planus (OLP), oral leukoplakia (OLK), and oral squamous cell carcinoma (OSCC) and to investigate the possibl...

    Qing-Mei Wang, Xue-Ying Huang, Wei-Qun Guan in Inflammation (2022)

  19. No Access

    Article

    Bioinformatic Analysis of the Potential Common Pathogenic Mechanisms for Psoriasis and Metabolic Syndrome

    The pathogeneses of psoriasis and metabolic syndrome are closely related; however, the underlying biological mechanisms are yet to be clarified. A psoriasis training set was downloaded from the Gene Expression...

    Yang Zhou, Lu Han, Ziting Wang, Runan Fang, Yue Wan, Zeyu Yang, Ning Guan… in Inflammation (2023)