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  1. Article

    Open Access

    Applications and prospects of cryo-EM in drug discovery

    Drug discovery is a crucial part of human healthcare and has dramatically benefited human lifespan and life quality in recent centuries, however, it is usually time- and effort-consuming. Structural biology ha...

    Kong-Fu Zhu, Chuang Yuan, Yong-Ming Du, Kai-Lei Sun… in Military Medical Research (2023)

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  2. No Access

    Article

    A luminescent Zn(II) coordination polymer for selective detection of Fe3+ ion that reverses the resistance of ovarian cancer to cisplatin

    By using the π-electron-rich organic ligand biphenyl-3,4′,5-tricarboxylic acid (H3BPT), the three-dimensional coordination polymer [Zn4(μ4-H2O)Cl2(BPT)2](DMF)2 was successfully prepared by the reaction of H3BPT a...

    Yue-Hua Shi, Yan Hu, Bei-Bei Jia… in Monatshefte für Chemie - Chemical Monthly (2019)

  3. Article

    Open Access

    Uncoating Mechanism of Carnation Mottle Virus Revealed by Cryo-EM Single Particle Analysis

    Genome uncoating is a prerequisite for the successful infection of plant viruses in host plants. Thus far, little is known about the genome uncoating of the Carnation mottle virus (CarMV). Here, we obtained two r...

    Chun-Yan Wang, Qin-Fen Zhang, Yuan-Zhu Gao, Li **e, Hong-Mei Li… in Scientific Reports (2015)

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  4. Article

    Open Access

    The ClpP protease homologue is required for the transmission traits and cell division of the pathogen Legionella pneumophila

    Legionella pneumophila, the intracellular bacterial pathogen that causes Legionnaires' disease, exhibit characteristic transmission traits such as elevated stress tolerance, shortened length and virulence during ...

    **ang-hui Li, Yong-lun Zeng, Ye Gao, **ao-cong Zheng, Qin-fen Zhang… in BMC Microbiology (2010)

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