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Article
Comparison of four confirmatory tests for the diagnosis of primary aldosteronism: Bayesian analysis in the absence of a gold standard
Captopril challenge test (CCT), seated saline infusion test (SSIT), oral sodium loading test (OSLT) and fludrocortisone suppression test (FST) are widely used diagnostic tests for primary aldosteronism (PA). T...
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Article
68Ga-pentixafor PET/CT in the localization diagnosis of primary aldosteronism concurrent subclinical cushing’s syndrsome: two case reports
Adrenal venous sampling (AVS) is recommended for subty** primary aldosteronism (PA). However, in cases of PA, concurrent subclinical Cushing’s syndrome (SCS) has the potential to confound AVS results. Pentix...
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Article
Trajectory prediction for fighter aircraft ground collision avoidance based on the model predictive control technique
Controlled flight into terrain accidents pose a significant threat to aviation safety, emphasizing the need for effective automatic ground collision avoidance system (Auto GCAS). However, the diversity and com...
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Article
Temporin-GHaR Peptide Alleviates LPS-Induced Cognitive Impairment and Microglial Activation by Modulating Endoplasmic Reticulum Stress
Neuroinflammation is considered an important factor that leads to cognitive impairment. Microglia play a crucial role in neuroinflammation, which leads to cognitive impairment. This study aimed at determining ...
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Article
Open AccessIdentification of four biotypes in temporal lobe epilepsy via machine learning on brain images
Artificial intelligence provides an opportunity to try to redefine disease subtypes based on similar pathobiology. Using a machine-learning algorithm (Subtype and Stage Inference) with cross-sectional MRI from...
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Article
Screening for primary aldosteronism on and off interfering medications
To determine whether antihypertensives will affect diagnostic accuracy of the aldosterone-to-renin ratio (ARR) to an extent that is clinically relevant.
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Article
Open AccessPrimary aldosteronism and lower-extremity arterial disease: a two-sample Mendelian randomization study
Primary aldosteronism (PA) is an adrenal disorder of autonomous aldosterone secretion which promotes arterial injury. We aimed to explore whether PA is causally associated with lower-extremity arterial disease...
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Article
Open AccessDeep immunophenoty** reveals clinically distinct cellular states and ecosystems in large-scale colorectal cancer
Determining the diverse cell types in the tumor microenvironment (TME) and their organization into cellular communities, is critical for understanding the biological heterogeneity and therapy of cancer. Here, ...
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Article
Open AccessTRAP-induced PAR1 expression with its mechanism during AMI in a rat model
Protease-activated receptor 1 (PAR1) is crucial in individuals with acute myocardial infarction (AMI). The continuous and prompt PAR1 activation mainly dependent on PAR1 trafficking is essential for the role o...
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Chapter and Conference Paper
Control Parameter Optimization for a Longitudinal Automatic Landing System via a Multi-objective Genetic Algorithm
It is challenging for control design and parameter optimization of a civil aircraft automatic landing system due to the complex application environment and high tracking precision requirement. In this paper, a...
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Article
Open AccessClinical analysis of neuromyelitis optica spectrum disease with area postrema syndrome as the initial symptom
The objective of this study was to report and discuss clinical analysis, including the diagnosis and treatment of 4 cases of neuromyelitis optica spectrum disease (NMOSD) with area postrema syndrome (APS) as t...
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Article
3BDO Alleviates Seizures and Improves Cognitive Function by Regulating Autophagy in Pentylenetetrazol (PTZ)-Kindled Epileptic Mice Model
3-benzyl-5-((2-nitrophenoxy) methyl)-dihydrofuran-2(3 H)-one (3BDO) is a mTOR agonist that inhibits autophagy. The main purpose of this study is to investigate the effects of 3BDO on seizure and cognitive func...
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Article
Deep reinforcement learning-based upset recovery control for generic transport aircraft
The aircraft loss-of-control problem has been a growing concern in civil aviation as it remains to be one of the major causes of fatal accidents. It is very difficult and challenging to design an upset recover...
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Article
Gain-scheduled anti-windup PID control for LPV systems under actuator saturation and its application to aircraft
To fill in the gap between theory and practice, this paper presents a gain-scheduled anti-windup proportional-integral-derivative (PID) control strategy for linear parameter-varying (LPV) systems with actuator...
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Article
Open AccessEfficacy of generic teriparatide and alendronate in Chinese postmenopausal women with osteoporosis: a prospective study
The efficacy of generic teriparatide in improving BMD at lumbar spine in patients with osteoporosis was similar to that of alendronate. It provided a new choice for osteoporosis treatment in Chinese population.
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Article
Open AccessHuman herpesvirus 6B infection in mesial temporal lobe epilepsy: a meta-analysis
Whether human herpesvirus 6B (HHV-6B) can affect mesial temporal lobe epilepsy (MTLE) remains controversial. The present meta-analysis was aimed to evaluate whether HHV-6B is significantly associated with MTLE.
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Article
LMI-based linear parameter varying PID control design and its application to an aircraft control system
To bridge the gap between real-world applications and theoretical achievements, this paper proposes a new synthesis approach of gain-scheduled proportional–integral–derivative (PID) control for linear paramete...
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Article
Open AccessEfficacy of Dulaglutide in Chinese Patients with Type 2 Diabetes and Different Glycemic Patterns: a Post-hoc Analysis of the Phase 3 AWARD-CHN2 Trial
We evaluated the effect of dulaglutide on the relative contributions of fasting glucose (FG) and postprandial glucose (PPG) to overall hyperglycemia in patients with type 2 diabetes (T2D), and assessed respons...
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Article
Connective profiles and antagonism between dynamic and static connectivity underlying generalized epilepsy
This study aims to characterize the connective profiles and the coupling relationship between dynamic and static functional connectivity (dFC and sFC) in large-scale brain networks in patients with generalized...
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Article
Correction to: Efficacy and acceptability of the S1P receptor in the treatment of multiple sclerosis: a meta-analysis
A Correction to this paper has been published: https://doi.org/10.1007/s10072-021-05137-x
