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Article
Estrogen Receptor Expression in Benign Breast Ductal Cells Obtained from Random Periareolar Fine Needle Aspiration Correlates with Menopausal Status and Cytomorphology Index Score
Estrogen receptor (ER) expression in breast epithelial cells has potential as a risk marker for development of breast cancer and as a response marker for preventive interventions.
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Article
Constant pH molecular dynamics (CpHMD) and molecular docking studies of CquiOBP1 pH-induced ligand releasing mechanism
The odorant binding protein of Culex quinquefasciatus (CquiOBP1), expressed on the insect antenna, is crucial for the investigation of trap** baited with oviposition semi-chemicals and controlling mosquito popu...
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Article
Influence of C-terminal tail deletion on structure and stability of hyperthermophile Sulfolobus tokodaii RNase HI
The C-terminus tail (G144-T149) of the hyperthermophile Sulfolobus tokodaii (Sto-RNase HI) plays an important role in this protein’s hyperstabilization and may therefore be a good protein stability tag. Detailed ...
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Article
Allocryptopine and benzyltetrahydropalmatine block hERG potassium channels expressed in HEK293 cells
Allocryptopine (ALL) is an alkaloid extracted from Corydalis decumbens (Thunb) Pers. Papaveraceae, whereas benzyltetrahydropalmatine (BTHP) is a derivative of tetrahydropalmatine extracted from Corydalis ambigua ...
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Article
Highlighting a π–π interaction: a protein modeling and molecular dynamics simulation study on Anopheles gambiae glutathione S-transferase 1-2
Cytosolic insect theta class glutathione S-transferases (GSTs) have not been studied completely and their physiological roles are unknown. A detailed understanding of Anopheles gambiae GST (Aggst1-2) requires an ...
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Article
Open AccessImpact of renal dysfunction on long-term outcomes of elderly patients with acute coronary syndrome: a longitudinal, prospective observational study
This study investigated the impact of renal dysfunction (RD) on long-term outcomes in elderly patients with acute coronary syndrome (ACS), and evaluated prognostic factors in elderly patients with ACS and RD.
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Article
Open AccessOccurrence of canine parvovirus in dogs from Henan province of China in 2009–2014
There is no information concerning the genotype of Canine parvovirus (CPV) currently circulating in Henan province, China. Therefore, the aim of the present study was to provide insights into the epidemiology ...
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Article
Open AccessOccurrence of Pasteurella multocida among pigs with respiratory disease in China between 2011 and 2015
Prior to the 1990s, P. multocida capsular serogroup A was the most prevalent in China, followed by serogroups B and D. Thirty years later, serogroup D became the most prevalent, followed by serogroups A and B. Ho...
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Article
The DEAD-Box RNA Helicase DDX1 Interacts with the Viral Protein 3D and Inhibits Foot-and-Mouth Disease Virus Replication
Foot-and-mouth disease virus (FMDV) can infect domestic and wild cloven-hoofed animals. The non-structural protein 3D plays an important role in FMDV replication and pathogenesis. However, the interaction partner...
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Article
Locally differentially private distributed algorithms for set intersection and union
This study designed schemes to obtain distributed multiset intersection and union by exploiting LDP. In the schemes, the private items in each data owner’s set were sanitized to satisfy ϵ-LDP, and meanwhile th...
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Article
Distribution, Risk Assessment, and Sources of Trace Metals in Surface Sediments from the Sea Area of Macao, South China
Due to rapid economic development in the Pearl River Delta, South China, trace metals pose a significant threat to the coastal ecosystems. In this study, we investigated the spatial distribution, contamination...
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Article
Foot-and-Mouth Disease Virus Inhibits RIP2 Protein Expression to Promote Viral Replication
Receptors interaction protein 2 (RIP2) is a specific adaptor molecule in the downstream of NOD2. The role of RIP2 during foot-and-mouth disease virus (FMDV) infection remains unknown. Here, our results showed ...
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Article
Mean estimation over numeric data with personalized local differential privacy
The fast development of the Internet and mobile devices results in a crowdsensing business model, where individuals (users) are willing to contribute their data to help the institution (data collector) analyze...
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Article
Major influence of hydroxyl and nitrate radicals on air pollution by environmentally persistent free radicals
Environmentally persistent free radicals are pollutants recently detected in most environmental matrices such as fly ash, aerosols, soils and sediments. Their generation and transformation is poorly known, not...
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Article
High atmospheric metal enrichment for a Saturn-mass planet
Atmospheric metal enrichment (that is, elements heavier than helium, also called ‘metallicity’) is a key diagnostic of the formation of giant planets1–3. The giant planets of the Solar System show an inverse rela...
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Article
A reflective, metal-rich atmosphere for GJ 1214b from its JWST phase curve
There are no planets intermediate in size between Earth and Neptune in our Solar System, yet these objects are found around a substantial fraction of other stars1. Population statistics show that close-in planets...