9 Result(s)

Article

Interseason waning of vaccine-induced hemagglutination inhibition antibody titers and contributing factors to pre-existing humoral immunity against influenza in community-dwelling older adults 75 years and older

Seasonal influenza causes significant morbidity and mortality with a disproportionately high disease burden in older adults. Strain-specific hemagglutination-inhibition (HAI) antibody titer is a well-establish...

Bettina Wunderlich, Thomas Laskow, Huifen Li, Li Zhang, Engle Abrams… in Immunity & Ageing (2023)

Article

Substitution of self-reported measures for objectively assessed grip strength and slow walk in the Physical Frailty Phenotype: ramifications for validity

Frailty assessment promises to identify older adults at risk for adverse consequences following stressors and target interventions to improve health outcomes. The Physical Frailty Phenotype (PFP) is a widely-s...

Karen Bandeen-Roche, **g Tian, Brian Buta, Jeremy Walston, Qian-Li Xue in BMC Geriatrics (2023)

Article

The combined effects of physical frailty and cognitive impairment on emergency department- versus direct-admission hospitalizations

We aimed to study whether physical frailty and cognitive impairment (CI) increase the risk of recurrent hospitalizations in older adults, independent of comorbidity, and disability.

Brian Buta, Ari B. Friedman, Shang-En Chung, Orla C. Sheehan… in BMC Geriatrics (2022)

Article

Agreement between standard and self-reported assessments of physical frailty syndrome and its components in a registry of community-dwelling older adults

The ability to identify frail older adults using a self-reported version of the physical frailty phenotype (PFP) that has been validated with the standard PFP could facilitate physical frailty detection in cli...

Brian Buta, Scott Zheng, Jackie Langdon, Bukola Adeosun… in BMC Geriatrics (2022)

Article

Aging metrics incorporating cognitive and physical function capture mortality risk: results from two prospective cohort studies

Aging metrics incorporating cognitive and physical function are not fully understood, hampering their utility in research and clinical practice. This study aimed to determine the proportions of vulnerable pers...

**ngqi Cao, Chen Chen, **gyun Zhang, Qian-Li Xue, Emiel O. Hoogendijk… in BMC Geriatrics (2022)

Article

The Framingham risk score is associated with incident frailty, or is it?

Cardiovascular disease (CVD) risk factors are individually associated with frailty. This study examined whether Framingham CVD risk score (FRS) as an aggregate measure of CVD risk is associated with incident f...

Hui Shi, Mei-Ling Ge, Birong Dong, Qian-Li Xue in BMC Geriatrics (2021)

Article

Sha** the next steps of research on frailty: challenges and opportunities

Ivan Aprahamian, Qian-Li Xue in BMC Geriatrics (2021)

Article

Develo** a sensor-based mobile application for in-home frailty assessment: a qualitative study

Frailty syndrome disproportionately affects older people, including 15% of non-nursing home population, and is known to be a strong predictor of poor health outcomes. There is a growing interest in incorporati...

Marcela D. Blinka, Brian Buta, Kevin D. Bader, Casey Hanley… in BMC Geriatrics (2021)

Article

Older adults’ perceptions and informational needs regarding frailty

Frailty has been recognized as an important medical syndrome in older adults. Growing literature supports the clinical application of frailty but US older adults’ perceptions of frailty have not been explored....

Nancy L. Schoenborn, Sarah E. Van Pilsum Rasmussen, Qian-Li Xue… in BMC Geriatrics (2018)