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  1. Article

    Open Access

    Whole exome sequencing analysis identifies genes for alcohol consumption

    Alcohol consumption is a heritable behavior seriously endangers human health. However, genetic studies on alcohol consumption primarily focuses on common variants, while insights from rare coding variants are ...

    Jujiao Kang, Yue-Ting Deng, Bang-Sheng Wu, Wei-Shi Liu, Ze-Yu Li in Nature Communications (2024)

  2. Article

    Open Access

    Nonlinear similarity characterisation and validation of dynamic response of ship stiffened plate structure under explosion load impacts

    The similarity test of ship stiffened plate structures under underwater explosions is a cost-effective and efficient method to evaluate the vitality of ships and guide the design of their shock resistance. Thi...

    Dongyan Shi, Jiuqiang Wang, Zhikai Wang, M. K. Helal Wasim in Scientific Reports (2024)

  3. Article

    Open Access

    Association between composite dietary antioxidant and bone mineral density in children and adolescents aged 8–19 years: findings from NHANES

    Dietary antioxidants may have beneficial effects on bone health, but it remains uncertain in children and adolescents. This study investigates the association of composite dietary antioxidant index (CDAI) with...

    Aiyong Cui, Juan Yan, Yuan Zeng, Baoqiang Shi, Long Cheng in Scientific Reports (2024)

  4. No Access

    Article

    Holistic food system innovation strategies can close up to 80% of China’s domestic protein gaps while reducing global environmental impacts

    China’s imports of livestock feed, particularly protein-rich feeds, pose challenges to global environmental sustainability. Achieving protein self-sufficiency for food and feed in China without exceeding envir...

    Hao Zhao, **angwen Fan, Zhaohai Bai, Lin Ma, Chao Wang, Petr Havlík in Nature Food (2024)

  5. Article

    Open Access

    Perturbation of METTL1-mediated tRNA N7- methylguanosine modification induces senescence and aging

    Cellular senescence is characterized by a decrease in protein synthesis, although the underlying processes are mostly unclear. Chemical modifications to transfer RNAs (tRNAs) frequently influence tRNA activity...

    Yudong Fu, Fan Jiang, **ao Zhang, Yingyi Pan, Rui Xu, **u Liang in Nature Communications (2024)

  6. Article

    Open Access

    Genome wide identification of novel DNA methylation driven prognostic markers in colorectal cancer

    Colorectal cancer (CRC) stands as a major contributor to cancer-related fatalities within China. There is an urgent need to identify accurate biomarkers for recurrence predicting in CRC. Reduced representation...

    Yuhua Ma, Yuanxin Li, Zhahong Wen, Yining Lai, Kulaixijiang Kamila in Scientific Reports (2024)

  7. Article

    Open Access

    Empagliflozin rescues pro-arrhythmic and Ca2+ homeostatic effects of transverse aortic constriction in intact murine hearts

    We explored physiological effects of the sodium-glucose co-transporter-2 inhibitor empagliflozin on intact experimentally hypertrophic murine hearts following transverse aortic constriction (TAC). Postoperativ...

    Qiang Wen, Rui Zhang, Kejun Ye, Jun Yang, Hangchuan Shi, Zhu Liu in Scientific Reports (2024)

  8. Article

    Open Access

    CircCDC42-encoded CDC42-165aa regulates macrophage pyroptosis in Klebsiella pneumoniae infection through Pyrin inflammasome activation

    The circular RNA (circRNA) family is a group of endogenous non-coding RNAs (ncRNAs) that have critical functions in multiple physiological and pathological processes, including inflammation, cancer, and cardio...

    Nana Xu, Jiebang Jiang, Fei Jiang, Guokai Dong, Li Meng, Meng Wang in Nature Communications (2024)

  9. Article

    Open Access

    Environment random interaction of rime optimization with Nelder-Mead simplex for parameter estimation of photovoltaic models

    As countries attach importance to environmental protection, clean energy has become a hot topic. Among them, solar energy, as one of the efficient and easily accessible clean energy sources, has received wides...

    **ge Shi, Yi Chen, Ali Asghar Heidari, Zhennao Cai, Huiling Chen in Scientific Reports (2024)

  10. Article

    Open Access

    Targeting the transmembrane cytokine co-receptor neuropilin-1 in distal tubules improves renal injury and fibrosis

    Neuropilin-1 (NRP1), a co-receptor for various cytokines, including TGF-β, has been identified as a potential therapeutic target for fibrosis. However, its role and mechanism in renal fibrosis remains elusive....

    Yinzheng Li, Zheng Wang, Huzi Xu, Yu Hong, Mengxia Shi, Bin Hu in Nature Communications (2024)

  11. Article

    Open Access

    Chromosome-level genome assembly of an oligophagous leaf beetle Ophraella communa (Coleoptera: Chrysomelidae)

    The leaf beetle Ophraella communa LeSage (Coleoptera: Chrysomelidae) is an effective biological control agent of the common ragweed. Here, we assembled a chromosome-level genome of the O. communa by combining Ill...

    Yi-Ting Wang, Yan Zhang, Chao Ma, Wei-Hua Ma, Li-Jun Cao, **-Cui Chen in Scientific Data (2024)

  12. Article

    Open Access

    Erythroid-intrinsic activation of TLR8 impairs erythropoiesis in inherited anemia

    Inherited non-hemolytic anemia is a group of rare bone marrow disorders characterized by erythroid defects. Although concerted efforts have been made to explore the underlying pathogenetic mechanisms of these ...

    **g Liang, Yang Wan, Jie Gao, Lingyue Zheng, **gwei Wang in Nature Communications (2024)

  13. Article

    Open Access

    Reformulating lipid nanoparticles for organ-targeted mRNA accumulation and translation

    Fully targeted mRNA therapeutics necessitate simultaneous organ-specific accumulation and effective translation. Despite some progress, delivery systems are still unable to fully achieve this. Here, we reformu...

    Kexin Su, Lu Shi, Tao Sheng, **nxin Yan, Lixin Lin, Chaoyang Meng in Nature Communications (2024)

  14. Article

    Open Access

    Longitudinal association between maternal cardiovascular health in pregnancy and child birth outcomes

    The American Heart Association has updated its definition of cardiovascular health (CVH) with a new framework known as Life's Essential 8 (LE8). Although gestational CVH assessment has been recommended, its si...

    Guangzhuang **g, Qian Wei, Jiaojiao Zou, Yunhui Zhang, Hui**g Shi in Scientific Reports (2024)

  15. Article

    Open Access

    A high security coding and anti-counterfeiting method based on the nonlinear magnetization response of superparamagnetic nanomaterials

    Traditional coding methods based on graphics and digital or magnetic labels have gradually decreased their anti-counterfeiting because of market popularity. This paper presents a new magnetic anti-counterfeiti...

    Shi Bai, Yuxi Lin, **aoju Wang, **aodan Zhang, Takashi Yoshida in Scientific Reports (2024)

  16. Article

    Open Access

    DCAF15 control of cohesin dynamics sustains acute myeloid leukemia

    The CRL4-DCAF15 E3 ubiquitin ligase complex is targeted by the aryl-sulfonamide molecular glues, leading to neo-substrate recruitment, ubiquitination, and proteasomal degradation. However, the physiological fu...

    Grant P. Grothusen, Renxu Chang, Zhendong Cao, Nan Zhou in Nature Communications (2024)

  17. Article

    Open Access

    The effect of classroom size and ceiling height on college students’ learning performance using virtual reality technology

    The physical characteristics of classrooms can significantly impact the physical and mental health as well as the learning performance of college students. This study investigates the effects of classroom size...

    Yalin Zhang, Chao Liu, Jiaxin Li, **aotong **g, **g Shi, Weijun Gao in Scientific Reports (2024)

  18. Article

    Open Access

    Experimental demonstration of tunable hybrid improper ferroelectricity in double-perovskite superlattice films

    Hybrid improper ferroelectricity can effectively avoid the intrinsic chemical incompatibility of electronic mechanism for multiferroics. Perovskite superlattices, as theoretically proposed hybrid improper ferr...

    Yaoxiang Jiang, Jianguo Niu, Cong Wang, Donglai Xue, **aohui Shi in Nature Communications (2024)

  19. Article

    Open Access

    Tamm-cavity terahertz detector

    Efficiently fabricating a cavity that can achieve strong interactions between terahertz waves and matter would allow researchers to exploit the intrinsic properties due to the long wavelength in the terahertz ...

    Xuecou Tu, Yichen Zhang, Shuyu Zhou, Wen**g Tang, Xu Yan in Nature Communications (2024)

  20. Article

    Open Access

    Dislocation response of ECC-RC composite supporting structures of tunnels passing through active fault

    To address the problems of the conventional composite supporting structures (CCSSs) such as insufficient anti-dislocation performance and deformation capacity, this study used Engineered Cementitious Composite...

    Shunguo Wang, Zude Ding, Chenghua Shi, Haibing Cai, Yusheng Chen in Scientific Reports (2024)

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