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  1. Article

    Open Access

    Empagliflozin rescues pro-arrhythmic and Ca2+ homeostatic effects of transverse aortic constriction in intact murine hearts

    We explored physiological effects of the sodium-glucose co-transporter-2 inhibitor empagliflozin on intact experimentally hypertrophic murine hearts following transverse aortic constriction (TAC). Postoperativ...

    Qiang Wen, Rui Zhang, Kejun Ye, Jun Yang, Hangchuan Shi, Zhu Liu in Scientific Reports (2024)

  2. Article

    Open Access

    Single-cell RNA sequencing of murine hearts for studying the development of the cardiac conduction system

    The development of the cardiac conduction system (CCS) is essential for correct heart function. However, critical details on the cell types populating the CCS in the mammalian heart during the development rema...

    Huiying Ren, **aolin Zhou, Jun Yang, Kun Kou, Tangting Chen, Zhaoli Pu in Scientific Data (2023)

  3. Article

    Open Access

    ALKBH2 inhibition alleviates malignancy in colorectal cancer by regulating BMI1-mediated activation of NF-κB pathway

    The alkB homolog 2, alpha-ketoglutarate-dependent dioxygenase (ALKBH2) gene is involved in DNA repair and is expressed in different types of malignancies. However, the role of ALKBH2 in colorectal carcinoma (C...

    Bingxin Ke, Kejun Ye, Shaobing Cheng in World Journal of Surgical Oncology (2020)