8,975 Result(s)
within
Qi** Shi
Life Sciences
-
Article
Diversity and environmental determinants of aquatic plants across China
Aquatic plants play an important role in aquatic systems. A comprehensive understanding of their spatial distribution may help to develop biodiversity conservation plans. This work investigated the spatial dis...
-
Article
Comprehensive Insights into the Health Effects of Selenium Exposure and Supplementation Among the Chinese Community Middle-Aged and Elderly: a Combined Retrospective Cohort Study and Intervention Study
Selenium (Se) is an essential trace element for maintaining human health, for example, plays a crucial role in preventing aging-related diseases. However, most studies on the health effects of Se among the com...
-
Article
Pathogenesis of cardiovascular diseases: effects of mitochondrial CF6 on endothelial cell function
Cardiovascular disease (CVD) stands as a predominant global cause of morbidity and mortality, necessitating effective and cost-efficient therapies for cardiovascular risk reduction. Mitochondrial coupling fact...
-
Article
Open AccessPublisher Correction: Restrained Mitf-associated autophagy by Mulberroside A ameliorates osteoclastogenesis and counteracts OVX-Induced osteoporosis in mice
-
Article
Open AccessCorrection: Recruitment of LEF1 by Pontin chromatin modifier amplifies TGFBR2 transcription and activates TGFβ/SMAD signalling during gliomagenesis
-
Article
Phylogenomics, divergence times and notes of orders in Basidiomycota
Basidiomycota is one of the major phyla in the fungal tree of life. The outline of Basidiomycota provides essential taxonomic information for researchers and workers in mycology. In this study, we present a ti...
-
Article
Cold tolerance SNPs and candidate gene mining in the soybean germination stage based on genome-wide association analysis
Three QTLs associated with low-temperature tolerance were identified by genome-wide association analysis, and 15 candidate genes were identified by haplotype analysis and gene expression analyses.
-
Article
Growth and Transcriptional Regulation of Camellia sinensis Planted in Understory Mode Revealed by Transcriptomic, Metagenomic, and Machine-Vision Analyses
Camellia sinensis is a significant economic and medical plant. The plant is short and thrives in shaded environments, making it suitable for cultivation under forest canopies. However, the mechanisms governing th...
-
Article
Open AccessNew mechanistic understanding of osteoclast differentiation and bone resorption mediated by P2X7 receptors and PI3K-Akt-GSK3β signaling
Osteoporosis is a global health issue characterized by decreased bone mass and microstructural degradation, leading to an increased risk of fractures. This study aims to explore the molecular mechanism by whic...
-
Article
Multi-omics reveal the regulation mechanism in response to freezing tolerance in Dendrobium catenatum
Main conclusion Freezing-tolerant Dendrobium catenatum cultivar responds to freezing stress by activating antioxidant enzyme systems and non-enzymatic systems including AsA and flavonoid biosynthetic pathways. De...
-
Article
Open AccessInhibition of PKC-δ retards kidney fibrosis via inhibiting cGAS-STING signaling pathway in mice
Kidney fibrosis is considered to be the ultimate aggregation pathway of chronic kidney disease (CKD), but its underlying mechanism remains elusive. Protein kinase C-delta (PKC-δ) plays critical roles in the co...
-
Article
Open AccessTracking the hologenome dynamics in aquatic invertebrates by the holo-2bRAD approach
The “hologenome” concept is an increasingly popular way of thinking about microbiome-host for marine organisms. However, it is challenging to track hologenome dynamics because of the large amount of material, ...
-
Article
Open AccessPhase separation of RNF214 promotes the progression of hepatocellular carcinoma
Hepatocellular carcinoma (HCC) is one of the most common malignant tumors, and the expression and function of an uncharacterized protein RNF214 in HCC are still unknown. Phase separation has recently been obse...
-
Article
Open AccessSalix species and varieties affect the molecular composition and diversity of soil organic matter
Most studies of the relationships between the composition of soil organic matter and plant cover have been carried out at the plant genera level. However, they have largely overlooked the potential effects tha...
-
Article
Open AccessNon-O blood types are associated with a greater risk of large artery atherosclerosis stroke and dysregulation of cholesterol metabolism: an observational study
Previous research on ABO blood types and stroke has been controversial, predominantly suggesting heightened risk of stroke in non-O blood types. Nonetheless, investigations into the correlation and underlying ...
-
Article
Open AccessMetaproteomics-informed stoichiometric modeling reveals the responses of wetland microbial communities to oxygen and sulfate exposure
Climate changes significantly impact greenhouse gas emissions from wetland soil. Specifically, wetland soil may be exposed to oxygen (O2) during droughts, or to sulfate (SO42-) as a result of sea level rise. How ...
-
Article
Author Correction: High-yield porphyrin production through metabolic engineering and biocatalysis
-
Article
Open Access5α-Epoxyalantolactone from Inula macrophylla attenuates cognitive deficits in scopolamine-induced Alzheimer’s disease mice model
Alzheimer’s disease (AD) is a complex neurodegenerative condition. 5α-epoxyalantolactone (5α-EAL), a eudesmane-type sesquiterpene isolated from the herb of Inula macrophylla, has various pharmacological effects. ...
-
Article
Open AccessCRISPR-based genome editing of a diurnal rodent, Nile grass rat (Arvicanthis niloticus)
Diurnal and nocturnal mammals have evolved distinct pathways to optimize survival for their chronotype-specific lifestyles. Conventional rodent models, being nocturnal, may not sufficiently recapitulate the bi...
-
Article
Open AccessPig blastocyst-like structure models from embryonic stem cells
Pluripotent stem cells have the potential to generate embryo models that can recapitulate developmental processes in vitro. Large animals such as pigs may also benefit from stem-cell-based embryo models for im...
