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Article
Open AccessLight modulates task-dependent thalamo-cortical connectivity during an auditory attentional task
Exposure to blue wavelength light stimulates alertness and performance by modulating a widespread set of task-dependent cortical and subcortical areas. How light affects the crosstalk between brain areas to tr...
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Systems Pharmacology and Pharmacogenomics for Drug Discovery and Development
Systems pharmacology involves the application of systems biology approaches, integrating high throughput experimental data from different experimental techniques such as genomics and proteomics involving compu...
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Article
Open AccessGenomic convergence and network analysis approach to identify candidate genes in Alzheimer's disease
Alzheimer’s disease (AD) is one of the leading genetically complex and heterogeneous disorder that is influenced by both genetic and environmental factors. The underlying risk factors remain largely unclear fo...
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Article
S-linked protein homocysteinylation: identifying targets based on structural, physicochemical and protein–protein interactions of homocysteinylated proteins
An elevated level of homocysteine, a thiol-containing amino acid is associated with a wide spectrum of disease conditions. A majority (>80 %) of the circulating homocysteine exist in protein-bound form. Homocy...