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11 Result(s)
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Professor L. I. Korochkin
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Book
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Chapter
Introduction
Two general principles in the relationship between genes and characters were already formulated in the 1930's. These principles are: (1) Every gene influences all of the traits of an organism, although its eff...
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Chapter
Conclusion
The individual development of the multicellular organisms is, as a final result, a matter of the growing heterogenization of the embryo, its division into complicating morphofunctional systems and specializing...
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Chapter
Nuclear-Cytoplasmic Interactions. The Basis for the Regulation of Gene Activity
As suggested by Morgan (1937) differential activity of nuclei is caused by differences in cytoplasmic environment; therefore, the first step of differentiation depends upon the nature of the cytoplasm in vario...
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Chapter
Genetic Heterogeneity and the Establishment of Tissue Systems During Development
The significance of trait expression at the tissue level during morphogenesis has already been demonstrated for the case of the early morphogenetic process of primary embryonic induction. The presumptive neuro...
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Chapter
The Organization of Systems Which Control Differential Gene Expression
Analysis of the genetic mechanisms of control of development is connected with the problem of regulation of gene activity. Naturally, cell specialization is due to an organized sequence of function of various ...
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Chapter
Differential Activity of Genes as a Basis for Cell Differentiation
The realization of hereditary information during ontogenesis is a multi-stage process and includes various levels of regulation—cell, tissue, and organism. A large number of genes act at each step of the devel...
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Chapter
The Phenomenon of Allelic Exclusion
In the previous chapters the various degrees of phenotypic expression of maternal and paternal biochemical traits were discussed. However, extreme cases are known when one of the parental characteristics is no...
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Chapter
Functional-Genetic Mosaicism in Cell Population
One of the important results of nuclear-cytoplasmic interactions is the realization of the complex processes which caused cell determination—the main event in ontogenesis. In discussing cell determination in h...
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Chapter
Genetic Regulation of Ontogenesis on the Organismal Level
As mentioned by Smalgausen (1938) “…the endocrine system is the basic integrating factor of the definite stages of morphogenesis.” The nervous system acts, in part, in the same direction. Actually, the conditi...
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Chapter
The Realization of Differential Gene Activity on the Post-Transcriptional, Translational, and Post-Translational Levels
Trait realization on the molecular level undergoes a number of stages, from transcription to RNA maturation and transport, then translation and, finally, the post- translational level.
