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  1. Article

    Open Access

    Transcriptional profiling of matched patient biopsies clarifies molecular determinants of enzalutamide-induced lineage plasticity

    The androgen receptor (AR) signaling inhibitor enzalutamide (enza) is one of the principal treatments for metastatic castration-resistant prostate cancer (CRPC). Several emergent enza clinical resistance mecha...

    Thomas C. Westbrook, **angnan Guan, Eva Rodansky, Diana Flores… in Nature Communications (2022)

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  2. Article

    Open Access

    Thrombotic thrombocytopenic purpura-hemolytic uremic syndrome (TTP-HUS): a 24-year clinical experience with 178 patients

    Thrombotic thrombocytopenic purpura and the hemolytic uremic syndrome (TTP-HUS) are related and uncommon disorders with a high fatality and complication rate if untreated. Plasma exchange therapy has been show...

    Mark Levandovsky, Danielle Harvey, Primo Lara, Ted Wun in Journal of Hematology & Oncology (2008)

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  3. No Access

    Article

    Oblimersen and α-interferon in metastatic renal cancer: a phase II study of the California Cancer Consortium

    Oblimersen is an 18-base oligodeoxynucleotide encoding antisense to the gene for bcl-2, an anti-apoptotic protein that is upregulated in renal and other cancers. This study was designed to evaluate the combina...

    Kim Margolin, Timothy W. Synold, Primo Lara… in Journal of Cancer Research and Clinical On… (2007)