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Article
Efficient assembly of a synthetic attenuated SARS-CoV-2 genome in Saccharomyces cerevisiae using multi-copy yeast vectors
Saccharomyces cerevisiae has been demonstrated to be an excellent platform for the multi-fragment assembly of large DNA constructs through its powerful homologous recombination ability. These assemblies have inva...
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Article
Conversion after laparoscopic cholecystectomy in England
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Article
Lymph Node Involvement and Surgical Approach in Parathyroid Cancer
The best surgical approach to parathyroid cancer is disputed. Recommendations vary and are built on incoherent evidence. High rates of recurrence and death require an in-depth review of underlying findings.
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Article
Letter to the editor on article Subcutaneous lateral internal sphincterotomy (SLIS)—a safe technique for treatment of chronic anal fissure
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Article
Advancing the case for combined laparoscopic–colonoscopic polyp resection?
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Article
Open AccessSmall cell carcinoma of the anus: a case report
Small cell carcinoma of the anus is a very rare but aggressive tumour. We present a case of a 60-year old lady with small cell carcinoma of the anus. She had no metastatic disease on presentation. She had chem...
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Article
Open AccessManagement of an incidentally found large adrenal myelolipoma: a case report
Adrenal myelolipoma is a rare benign neoplasm composed of mature adipose and hematopoietic tissue. Most lesions are small, unilateral and asymptomatic, discovered incidentally at autopsy or on imaging studies ...
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Article
Open AccessComplications of spilled gallstones following laparoscopic cholecystectomy: a case report and literature overview
Gallbladder perforation is common and occurs in 6 to 40% of laparoscopic cholecystectomy procedures. In up to a third of these cases, stones are not retrieved and complications can arise many years post-operat...
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Article
Open AccessPneumococcal sepsis presenting as acute compartment syndrome of the lower limbs: a case report
Acute compartment syndrome is a surgical emergency requiring immediate fasciotomy. Spontaneous onset of acute compartment syndrome of the lower limbs is rare. We present a very rare case of pneumococcal sepsis...
