Skip to main content

4 Result(s)

within Prajakti A. Kothare Remove this filter

and

  1. Article

    Open Access

    An Integrated Strategy for Implementation of Dried Blood Spots in Clinical Development Programs

    Dried blood spot (DBS) sample collection has gained increased interest across the pharmaceutical industry as a potential alternative to plasma for pharmacokinetic (PK) evaluations. However, regulatory guidelin...

    Prajakti A. Kothare, Kevin P. Bateman, Marissa Dockendorf, Julie Stone… in The AAPS Journal (2016)

    Download PDF (1325 KB) View Article

  2. Article

    Open Access

    Effect of exenatide on the pharmacokinetics of a combination oral contraceptive in healthy women: an open-label, randomised, crossover trial

    Consistent with its effect on gastric emptying, exenatide, an injectable treatment for type 2 diabetes, may slow the absorption rate of concomitantly administered oral drugs resulting in a decrease in maximum ...

    Prajakti A Kothare, Mary E Seger, Justin Northrup… in BMC Clinical Pharmacology (2012)

    Download PDF (452 KB) View Article

  3. Article

    D2 Receptor Occupancy of Olanzapine Pamoate Depot Using Positron Emission Tomography: An Open-label Study in Patients with Schizophrenia

    A long-acting depot formulation of olanzapine that sustains plasma olanzapine concentrations for over a month after a single injection is currently under development. This multicenter, open-label study explored D

    David Mamo, Shitij Kapur, Matcheri Keshavan, Marc Laruelle… in Neuropsychopharmacology (2008)

    Download PDF (148 KB) View Article

  4. No Access

    Article

    The Intestinal Uptake of Phenol from Micellar Systems Does Not Conform to the Aqueous Transfer Model

    Purpose. To evaluate the aqueous transfer model as the mechanismfor the micelle-mediated uptake of phenol in the rat in situ intestinalperfusion model.

    Prajakti A. Kothare, Cheryl L. Zimmerman in Pharmaceutical Research (2000)