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  1. Article

    Author Correction: REV-ERB in GABAergic neurons controls diurnal hepatic insulin sensitivity

    Guolian Ding, **n Li, **nguo Hou, Wenjun Zhou, Yingyun Gong, Fuqiang Liu… in Nature (2021)

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    Article

    REV-ERB in GABAergic neurons controls diurnal hepatic insulin sensitivity

    Systemic insulin sensitivity shows a diurnal rhythm with a peak upon waking1,2. The molecular mechanism that underlies this temporal pattern is unclear. Here we show that the nuclear receptors REV-ERB-α and REV-E...

    Guolian Ding, **n Li, **nguo Hou, Wenjun Zhou, Yingyun Gong, Fuqiang Liu… in Nature (2021)

  3. Article

    Open Access

    HIV-1 viral protein R (Vpr) induces fatty liver in mice via LXRα and PPARα dysregulation: implications for HIV-specific pathogenesis of NAFLD

    HIV patients develop hepatic steatosis. We investigated hepatic steatosis in transgenic mice expressing the HIV-1 accessory protein Vpr (Vpr-Tg) in liver and adipose tissues, and WT mice infused with synthetic...

    Neeti Agarwal, Dinakar Iyer, Chiara Gabbi, Pradip Saha… in Scientific Reports (2017)

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  4. Article

    Open Access

    PLIN2 is a Key Regulator of the Unfolded Protein Response and Endoplasmic Reticulum Stress Resolution in Pancreatic β Cells

    Progressive pancreatic β cell failure underlies the transition of impaired glucose tolerance to overt diabetes; endoplasmic reticulum (ER) stress expedites β cell failure in this situation. ER stress can be el...

    Elaine Chen, Tsung Huang Tsai, Lan Li, Pradip Saha, Lawrence Chan… in Scientific Reports (2017)

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