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Article
Proteolytic inactivation of CXCL12 in the lungs and circulation of COVID-19 patients
The human chemokine stromal cell-derived factor-1 (SDF-1) or CXCL12 is involved in several homeostatic processes and pathologies through interaction with its cognate G protein-coupled receptor CXCR4. Recent re...
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Article
Open AccessClinical practices underlie COVID-19 patient respiratory microbiome composition and its interactions with the host
Understanding the pathology of COVID-19 is a global research priority. Early evidence suggests that the respiratory microbiome may be playing a role in disease progression, yet current studies report contradic...
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Article
Open AccessDiscriminating mild from critical COVID-19 by innate and adaptive immune single-cell profiling of bronchoalveolar lavages
How the innate and adaptive host immune system miscommunicate to worsen COVID-19 immunopathology has not been fully elucidated. Here, we perform single-cell deep-immune profiling of bronchoalveolar lavage (BAL...
