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Article
Open AccessGenome-wide association study of Alzheimer’s disease CSF biomarkers in the EMIF-AD Multimodal Biomarker Discovery dataset
Alzheimer’s disease (AD) is the most prevalent neurodegenerative disorder and the most common form of dementia in the elderly. Susceptibility to AD is considerably determined by genetic factors which hitherto ...
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Article
Open AccessOxytocin Receptors Regulate Social Preference in Zebrafish
With a strong tendency to socialise, the zebrafish is a useful model to study social behaviour, with implications for better treatments of social impairments, for instance in autism spectrum disorders. Althoug...
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Calcium Imaging in the Zebrafish
The zebrafish (Danio rerio) has emerged as a widely used model system during the last four decades. The fact that the zebrafish larva is transparent enables sophisticated in vivo imaging, including calcium imagin...
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Article
Open AccessCognitive medicine – a new approach in health care science
The challenges of today’s society call for more knowledge about how to maintain all aspects of cognitive health, such as speed/attention, memory/learning, visuospatial ability, language, executive capacity and...
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Article
Open AccessProteomic analyses of limbic regions in neonatal male, female and androgen receptor knockout mice
It is well-established that organizational effects of sex steroids during early development are fundamental for sex-typical displays of, for example, mating and aggressive behaviors in rodents and other specie...
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Article
Open AccessEffects of sex and gonadectomy on social investigation and social recognition in mice
An individual’s ability to recognise and pay attention to others is crucial in order to behave appropriately in various social situations. Studies in humans have shown a sex bias in sociability as well as soci...
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Article
Open AccessA Caged Ret Kinase Inhibitor and its Effect on Motoneuron Development in Zebrafish Embryos
Proto-oncogene tyrosine-protein kinase receptor RET is implicated in the development and maintenance of neurons of the central and peripheral nervous systems. Attaching activity-compromising photocleavable gro...
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Article
A novel ARC gene polymorphism is associated with reduced risk of Alzheimer’s disease
Alzheimer’s disease (AD) is the most common neurodegenerative disease, and is clinically characterized by cognitive disturbances and the accumulation of the amyloid β (Aβ) peptides in plaques in the brain. Rec...
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Single Cell Physiology
The possibility to control at specific times and specific places the activity of biomolecules (enzymes, transcription factors, RNA, hormones, etc.) is opening up new opportunities in the study of physiological...
