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Article
Open AccessThe clinical relevance of animal models in Sjögren’s syndrome: the interferon signature from mouse to man
Mouse models have been widely used to elucidate the pathogenic mechanisms of human diseases. The advantages of using these models include the ability to study different stages of the disease with particular re...
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Article
Open AccessAltered phenotype and Stat1 expression in Toll-like receptor 7/8 stimulated monocyte-derived dendritic cells from patients with primary Sjögren’s syndrome
Dendritic cells (DC) are the most potent antigen-presenting cells of the immune system, involved in both initiating immune responses and maintaining tolerance. Dysfunctional and via toll-like receptor (TLR) li...
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Article
Konventionelle und virtuelle Simulation bei der Retrobulbärbestrahlung
Zur Therapie der endokrinen Orbitopathie wird die Bestrahlung der Retrobulbärräume eingesetzt. Das Zielvolumen umschließt die Orbita und die äußeren Augenmuskeln. Mit der CT-Simulation läßt sich das Ergebnis ...