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Article
Open AccessA randomized prospective cross over study on the effects of medium cut-off membranes on T cellular and serologic immune phenotypes in hemodialysis
Extended cut-off filtration by medium cut-off membranes (MCO) has been shown to be safe in maintenance hemodialysis (HD). The notion of using them for the control of chronic low-grade inflammation and positive...
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Article
Open AccessSubstitution of perioperative albumin deficiency disorders (SuperAdd) in adults undergoing vascular, abdominal, trauma, or orthopedic surgery: protocol for a randomized controlled trial
Hypalbuminemia is associated with numerous postoperative complications, so a perioperative albumin substitution is often considered. The objective of SuperAdd is to investigate whether substitution of human al...
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Article
Open AccessHyperkalemia in patients treated with endoradiotherapy combined with amino acid infusion is associated with severe metabolic acidosis
Amino acid co-infusion for renal protection in endoradiotherapy (ERT) applied as prostate-specific membrane antigen (PSMA)-targeted radioligand therapy (RLT) or peptide receptor radionuclide therapy (PRRT) has...
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Article
C-terminal agrin fragment (CAF) as a serum biomarker for residual renal function in peritoneal dialysis patients
C-terminal agrin fragment (CAF, size 22 kDa) is a promising new biomarker for kidney function. This study evaluated the usefulness of CAF as a serum biomarker for residual renal function (RRF) in patients und...
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Article
Open AccessEvaluation of the Hepa Wash®treatment in pigs with acute liver failure
Mortality of patients with acute liver failure (ALF) is still unacceptably high. Available liver support systems are still of limited success at improving survival. A new type of albumin dialysis, the Hepa Wash® ...
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Protocol
PROTIS: Use of Combined Biomarkers for Providing Diagnostic Information on Disease States
We describe herein PROTIS, a software package that allows for the combination of urine biomarkers (proteins, small molecules, cells) to provide accurate diagnostic information on renal disease states. Such an ...
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Article
Steroid Synthesis Inhibition with Ketoconazole and its Effect upon the Regulation of the Hypothalamus–Pituitary–Adrenal System in Healthy Humans
Steroid synthesis inhibitors are commonly used in the treatment of patients with Cushing's disease, but may also improve psychopathology in hypercortisolemic depressed patients. Since glucocorticoids exert a n...
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Chapter
Cremophor EL Alters Uptake, Retention, Distribution, and Toxicity of the Boron Containing Ether Lipid
We have proposed boron-containing ether lipids as boron carriers for BNCT; because these are expected to accumulate selectively in tumors.1 These properties depend most probably on the absence of an ether lipid-c...
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Article
Beeinflussung der Testosteron-Messung durch das Sexual-Hormon-bindende Globulin in Radioimmunoassays ohne Extraktion