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Article
Open AccessIslet autoimmunity in human type 1 diabetes: initiation and progression from the perspective of the beta cell
Type 1 diabetes results from the poorly understood process of islet autoimmunity, which ultimately leads to the loss of functional pancreatic beta cells. Mounting evidence supports the notion that the activati...
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Article
Open AccessEstimated blood loss in pregnant women with cardiac disease compared with low risk women: a restrospective cohort study
Women with cardiac disease are thought to be at increased risk of post-partum haemorrhage. We sought to assess the estimated blood loss (EBL) in our cohort of women with and without cardiac disease (CD) in a q...
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Article
Open AccessCorrection to: Pregnancy outcomes in patients with a fontan circulation and proposal for a risk-scoring system: single Centre experience
The original version of this article [1] unfortunately included an error to an author’s name. Author Aliyah Choudhary was erroneously presented as Aliyah Chaudhary.
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Article
Open AccessPregnancy outcomes in patients with a fontan circulation and proposal for a risk-scoring system: single centre experience
Pregnancy in women with Fontan physiology poses a significant management challenge and is deemed high risk. The aim of this study is to describe short and long-term pregnancy outcomes in women who have undergo...
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Article
Open AccessDistinct roles of KAP1, HP1 and G9a/GLP in silencing of the two-cell-specific retrotransposon MERVL in mouse ES cells
In mouse embryonic stem cells (mESCs), transcriptional silencing of numerous class I and II endogenous retroviruses (ERVs), including IAP, ETn and MMERVK10C, is dependent upon the H3K9 methyltransferase (KMTas...
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Article
112 ELEVATION OF PROSTAGLANDIN LEVELS IN PREGNANCIES COMPLICATED BY PREMATURE RUPTURE OF THE MEMBRANES (PROM)
Paired maternal and fetal prostaglandin levels were estimated in patients with pregnancies complicated by premature rupture of the membranes (PROM). Their results were compared to those of controls who had pre...
