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  1. Article

    Open Access

    Microbial-derived imidazole propionate links the heart failure-associated microbiome alterations to disease severity

    Interactions between the gut microbiota, diet, and host metabolism contribute to the development of cardiovascular disease, but a firm link between disease-specific gut microbiota alterations and circulating m...

    Sajan C. Raju, Antonio Molinaro, Ayodeji Awoyemi, Silje F. Jørgensen in Genome Medicine (2024)

  2. Article

    Riboflavin status modifies the effects of methylenetetrahydrofolate reductase (MTHFR) and methionine synthase reductase (MTRR) polymorphisms on homocysteine

    Methylenetetrahydrofolate reductase (MTHFR) and methionine synthase reductase (MTRR), riboflavin-dependent enzymes, participate in homocysteine metabolism. Reported effects of riboflavin status on the associat...

    Carlos J. García-Minguillán, Joan D. Fernandez-Ballart in Genes & Nutrition (2014)

  3. No Access

    Article

    Functional inference of the methylenetetrahydrofolate reductase 677 C > T and 1298A > C polymorphisms from a large-scale epidemiological study

    Two functional single nucleotide polymorphisms, 677C > T and 1298A > C have been described for the methylenetetrahydrofolate (MTHFR) gene. Both are associated with reduced enzyme activity in vitro. For the 677...

    Arve Ulvik, Per M. Ueland, Åse Fredriksen, Klaus Meyer in Human Genetics (2007)