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Open AccessThe potential pathogenic roles of S100A8/A9 and S100A12 in patients with MPO-ANCA-positive vasculitis
The significance of S100A8/A9 and S100A12 in anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) has not been clarified. This study was dedicated to exploring the potential pathogenic roles...
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Article
Exposure parameters and health risk of Cryptosporidium and Giardia in the recreational water activities for urban residents in China
Knowledge gaps in the exposure parameters for recreational water activities make quantitative risk assessment related to water recreation difficult. Therefore, the annual exposure frequency and single exposure...
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Article
Open AccessEffects and mechanism of platelet-rich plasma on military drill injury: a review
Military drill injury is a significant part of military medical research. The increase of training intensity and changes in training methods lead to differences in injury types. The ideal therapeutic modality ...
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Open AccessPathological severity determines the renal recovery for anti-myeloperoxidase antibody-associated vasculitis requiring dialysis at disease onset: a retrospective study
Many patients with anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) need dialysis at disease onset due to severe kidney injury. Determining whether they can become dialysis independent i...
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Article
High serum hepcidin is associated with the occurrence of anemia in anti-myeloperoxidase antibody-associated vasculitis with normal kidney function: a cross-sectional study
The etiology of anemia in antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) has not been elucidated. In this cross-sectional study, we tried to investigate the relationship between serum h...
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Article
Open AccessMalignant ureteral obstruction: experience and comparative analysis of metallic versus ordinary polymer ureteral stents
To study the outcome and experience of using metallic stents in treating patients with malignant ureteral obstruction (MUO).
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Article
Elimination of viruses from domestic wastewater: requirements and technologies
Domestic wastewater contains various pathogens, which, if not sufficiently eliminated, may enter the receiving water bodies and cause water-transmitted diseases. Among the waterborne pathogens, viruses may occ...
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Article
Open AccessC-reactive protein enhances activation of coagulation system and inflammatory response through dissociating into monomeric form in antineutrophil cytoplasmic antibody-associated vasculitis
C-reactive protein (CRP) exerts prothrombotic effects through dissociating from pentameric CRP (pCRP) into modified or monomeric CRP (mCRP). However, although the high prevalence of venous thromboembolism (VTE...
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Article
Open AccessAn investigation of drug-resistant Acinetobacter baumannii infections in a comprehensive hospital of East China
To investigate the drug resistant gene profiles and molecular ty** of Acinetobacter baumannii isolates collected from clinical specimens in a comprehensive hospital, Jiangsu province.
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Article
Open AccessUrinary kidney injury molecule-1 is related to pathologic involvement in IgA nephropathy with normotension, normal renal function and mild proteinuria
IgA nephropathy (IgAN) may progress to renal failure for some patients without any clinical risk factors and it is not unusual to find severe pathologic damage in clinically mild IgAN. We therefore investigate...
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Article
IgG4-related membranous nephropathy with high blood and low urine IgG4/IgG ratio: a case report and review of the literature
Membranous nephropathy (MN) is a rare manifestation of IgG4-related disease. Interestingly, the significance of IgG4 has also been documented in idiopathic MN (IMN). Previous studies reported that urine IgG4/I...
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Article
Open AccessEpitope analysis of anti-myeloperoxidase antibodies in propylthiouracil-induced antineutrophil cytoplasmic antibody-associated vasculitis
Increasing evidence has suggested that linear epitopes of antineutrophil cytoplasmic antibody (ANCA) directed to myeloperoxidase (MPO) might provide clues to the pathogenesis of propylthiouracil (PTU)-induced ...
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Article
Antineutrophil cytoplasmic autoantibody-associated vasculitis in Chinese patients
Antineutrophil cytoplasmic autoantibody (ANCA)-associated vasculitis (AAV) is a common autoimmune disease in China. AAVs in the majority of Chinese patients are microscopic polyangiitis with antigenicity to my...
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Open AccessInfluence of variable domain glycosylation on anti-neutrophil cytoplasmic autoantibodies and anti-glomerular basement membrane autoantibodies
The pathophysiological significance of variable region glycosylation of autoantibodies is still unclear. In the current study, the influence of the variable region N-linked oligosaccharides on the reactivity o...
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Open AccessThe association of HLA-DQB1, -DQA1 and -DPB1 alleles with anti- glomerular basement membrane (GBM) disease in Chinese patients
Human leukocyte antigen (HLA) alleles are associated with many autoimmune diseases, including anti-glomerular basement membrane (GBM) disease. In our previous study, it was demonstrated that HLA-DRB1*1501 was ...
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Article
The Existence of Silnikov's Orbit in Four-dimensional Duffing's Systems
The existence of Silnikov's orbits in a four-dimensional dynamical system is discussed. The existence of Silnikov's orbit resulting in chaotic dynamics is established by the fiber structure of invariant manifo...
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Article
Bifurcation and Chaos in a Weakly Nonlinear System Subjected to Combined Parametric and External Excitation
In this paper the dynamics of a weakly nonlinear system subjected to combined parametric and external excitation are discussed. The existence of transversal homoclinic orbits resulting in chaotic dynamics and ...
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Article
Truncation Analysis for the Derivative Schrödinger Equation
The truncation equation for the derivative nonlinear Schrödinger equation has been discussed in this paper. The existence of a special heteroclinic orbit has been found by using geometrical singular perturbati...