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  1. Article

    Open Access

    Inhalable hybrid nanovaccines with virus-biomimetic structure boost protective immune responses against SARS-CoV-2 variants

    Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), with different antigenic variants, has posed a significant threat to public health. It is urgent to develop inhalable vaccines, instead of injectab...

    Shuqi Wang, Peiyang Ding, Lingli Shen, Daopeng Fan in Journal of Nanobiotechnology (2024)

  2. Article

    Open Access

    Double-layered N-S1 protein nanoparticle immunization elicits robust cellular immune and broad antibody responses against SARS-CoV-2

    The COVID-19 pandemic is a persistent global threat to public health. As for the emerging variants of SARS-CoV-2, it is necessary to develop vaccines that can induce broader immune responses, particularly vacc...

    Ruiqi Li, Zejie Chang, Hongliang Liu, Yanan Wang in Journal of Nanobiotechnology (2024)

  3. No Access

    Article

    A duplex TaqMan probe-based real-time PCR method for rapid detection and differentiation of the classical and VB strains of human immunodeficiency virus

    Ai** Wang, Haili Wang, Jianguo Zhao, Yumei Chen in Science China Life Sciences (2024)

  4. Article

    Electrochemical immunosensor nanoarchitectonics with the Ag-rGO nanocomposites for the detection of receptor-binding domain of SARS-CoV-2 spike protein

    As the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) poses a grave threat to human life and health, it is essential to develop an efficient and sensitive detection method to identify infected in...

    Ai** Wang, Yuya Li, in Journal of Solid State Electrochemistry (2023)

  5. Article

    Screening and identification of B cell epitope of the nucleocapsid protein in SARS-CoV-2 using the monoclonal antibodies

    Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the virus that causes the coronavirus disease (COVID-19). It is confirmed that nucleocapsid (N) protein is closely related to viral pathogenesis,...

    Yuanyuan Tian, Gai** Zhang, Hongliang Liu in Applied Microbiology and Biotechnology (2022)

  6. No Access

    Article

    Gold nanoparticles enhance immune responses in mice against recombinant classical swine fever virus E2 protein

    To create a novel subunit vaccine that used AuNPs as carriers to enhance immune responses in mice against recombinant classical swine fever virus E2 protein (CSFV E2).

    Yafei Li, Qianyue **, Peiyang Ding, Wen Zhou, Yongxiao Chai in Biotechnology Letters (2020)

  7. No Access

    Article

    A strip test for the optical determination of influenza virus H3 subtype using gold nanoparticle coated polystyrene latex microspheres

    A strip test is described for the optical determination of influenza virus H3 subtype. It utilizes gold nanoparticle (AuNP) coated polystyrene latex microspheres (PS) as the label and a sandwich format. The Au...

    **ao Liu, Jifei Yang, Qingmei Li, Yinbiao Wang, Yanhong Wang, Ge Li in Microchimica Acta (2020)

  8. Article

    Open Access

    Molecular epidemiology of hydropericardium syndrome outbreak-associated serotype 4 fowl adenovirus isolates in central China

    In several parts of China, there have been a large number of hydropericardium syndrome (HPS) outbreaks caused by serotype 4 fowl adenovirus (FAdV­4) in broiler chickens since 2015. These outbreak-associated FA...

    Teng Zhang, Qianyue **, Peiyang Ding, Yinbiao Wang, Yongxiao Chai in Virology Journal (2016)

  9. Article

    Open Access

    Rescue and evaluation of a recombinant PRRSV expressing porcine Interleukin-4

    The current vaccines for porcine reproductive and respiratory syndrome virus (PRRSV) have failed to provide broad protection against infection by various strains of PRRSV. Porcine Interleukin-4 (pIL-4) plays a...

    Zhijun Li, Gang Wang, Yan Wang, Chong Zhang, **nglong Wang in Virology Journal (2015)