Skip to main content

7 Result(s)

within Peidong Han Remove this filter

and

  1. Article

    Open Access

    Cardiac cell type-specific responses to injury and contributions to heart regeneration

    Heart disease is the leading cause of mortality worldwide. Due to the limited proliferation rate of mature cardiomyocytes, adult mammalian hearts are unable to regenerate damaged cardiac muscle following injur...

    Weijia Zhang, **xiu Liang, Peidong Han in Cell Regeneration (2021)

    Download PDF (862 KB) View Article

  2. No Access

    Article

    Coordinating cardiomyocyte interactions to direct ventricular chamber morphogenesis

    A complex interplay involving Notch- and Erbb2-mediated signalling between cardiomyocytes guides the morphogenesis of the ventricular wall.

    Peidong Han, Joshua Bloomekatz, Jie Ren, Ruilin Zhang, Jonathan D. Grinstein… in Nature (2016)

  3. No Access

    Article

    Surface-blended texturing of medical needles for friction reduction using a picosecond laser

    The success of percutaneous procedures depends on the accuracy of the medical needle insertion. Reducing the insertion force and using better needle visualization during needle insertion can reduce needle plac...

    **ngsheng Wang, Peidong Han, Min Kang, Kornel Ehmann in Applied Physics A (2016)

  4. Article

    Hydrogen peroxide primes heart regeneration with a derepression mechanism

    While the adult human heart has very limited regenerative potential, the adult zebrafish heart can fully regenerate after 20% ventricular resection. Although previous reports suggest that developmental signali...

    Peidong Han, **ao-Hai Zhou, Nannan Chang, Cheng-Lu **ao, Shouyu Yan… in Cell Research (2014)

    Download PDF (8197 KB) View Article

  5. No Access

    Article

    In vivo cardiac reprogramming contributes to zebrafish heart regeneration

    A cardiac injury study in zebrafish reveals the plasticity of heart cell lineages as shown by a Notch-dependent transdifferentiation of atrial to ventricular cardiomyocytes, regenerating a cell type that is da...

    Ruilin Zhang, Peidong Han, Hongbo Yang, Kunfu Ouyang, Derek Lee, Yi-Fan Lin… in Nature (2013)

  6. No Access

    Article

    Targeted ablation of the histidine-rich Ca2+-binding protein (HRC) gene is associated with abnormal SR Ca2+-cycling and severe pathology under pressure-overload stress

    The histidine-rich Ca2+-binding protein (HRC) is located in the lumen of the sarcoplasmic reticulum (SR) and exhibits high-capacity Ca2+-binding properties. Overexpression of HRC in the heart resulted in impaired...

    Chang Sik Park, Shan Chen, Hoyong Lee, Hyeseon Cha… in Basic Research in Cardiology (2013)

  7. No Access

    Protocol

    Zebrafish Cardiac Injury and Regeneration Models: A Noninvasive and Invasive In Vivo Model of Cardiac Regeneration

    Despite current treatment regimens, heart failure still remains one of the leading causes of morbidity and mortality in the world due to failure to adequately replace lost ventricular myocardium from ischemia-...

    Michael S. Dickover, Ruilin Zhang, Peidong Han… in Wound Regeneration and Repair (2013)