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    Chapter

    The Effects of Hypertension on Cerebral Artery Structure and Function, and Cerebral Blood Flow

    Careful regulation of cerebral blood flow is required to maintain proper brain function. The cerebral arteries are particularly sensitive to the effects of hypertension, which alters the arteries in a manner t...

    Paulo W. Pires, Anne M. Dorrance in Hypertension and the Brain as an End-Organ Target (2016)

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    Article

    Direct regulation of blood pressure by smooth muscle cell mineralocorticoid receptors

    The mineralocorticoid receptor, targeted by drugs commonly used to treat hypertension, is generally thought to contribute to hypertension by altering kidney function. Using mice lacking the mineralocorticoid r...

    Amy McCurley, Paulo W Pires, Shawn B Bender, Mark Aronovitz… in Nature Medicine (2012)