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Open AccessModified One Anastomosis Gastric Bypass Following Sleeve Gastrectomy for Severe Reflux and Delayed Gastric Emptying: A Prospective Trial with Clinical and Physiological Outcome Measures
Gastro-esophageal reflux (GORD) following sleeve gastrectomy (SG) is a central challenge, and precise indications for revisional surgery or the physiology have not been precisely defined. We aimed to determine...
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Open AccessEmerging multi-port soft tissue robotic systems: a systematic review of clinical outcomes
Multiple novel multi-port robotic surgical systems have been introduced into clinical practice. This systematic review aims to evaluate the clinical outcomes of these novel robotic systems to conventional lapa...
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Open AccessBariatric Surgery Efficiency, Safety and Health Outcomes in Government Versus Privately Funded Hospitals
This study aims to determine if the hospital efficiency, safety and health outcomes are equal in patients who receive bariatric surgery in government-funded hospitals (GFH) versus privately funded hospitals (P...
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Open AccessComprehensive Analysis of Improvements in Health-Related Quality of Life and Establishment of QALY Gains in a Government-Funded Bariatric Surgical Program with 5-Year Follow-up
Bariatric surgery is an efficacious intervention for substantial and sustained weight reduction in individuals with morbid obesity resulting in health improvements. However, the changes to a patient’s health r...
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Open AccessDeep proteomic profiling unveils arylsulfatase A as a non-alcoholic steatohepatitis inducible hepatokine and regulator of glycemic control
Non-alcoholic steatohepatitis (NASH) and type 2 diabetes are closely linked, yet the pathophysiological mechanisms underpinning this bidirectional relationship remain unresolved. Using proteomic approaches, we...
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Correction to: Improving Compliance with Very Low Energy Diets (VLEDs) Prior to Bariatric Surgery—A Randomized Controlled Trial of Two Formulations
In the original article the name of author Alexandra Klejn was misspelled.
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Open AccessBetter governance, better access: practising responsible data sharing in the METADAC governance infrastructure
Genomic and biosocial research data about individuals is rapidly proliferating, bringing the potential for novel opportunities for data integration and use. The scale, pace and novelty of these applications ra...
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Open AccessThe ECOUTER methodology for stakeholder engagement in translational research
Because no single person or group holds knowledge about all aspects of research, mechanisms are needed to support knowledge exchange and engagement. Expertise in the research setting necessarily includes scien...
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Author Reply—Bariatric Surgery and Liver Function Tests in Nonalcoholic Fatty Liver Disease
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Erratum to: Laparoscopic Adjustable Gastric Banding in Patients With Unexpected Cirrhosis: Safety and Outcomes
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Open AccessRealizing the promise of population biobanks: a new model for translation
The promise of science lies in expectations of its benefits to societies and is matched by expectations of the realisation of the significant public investment in that science. In this paper, we undertake a metho...
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Open AccessLongitudinal variance components models for systolic blood pressure, fitted using Gibbs sampling
This paper describes an analysis of systolic blood pressure (SBP) in the Genetic Analysis Workshop 13 (GAW13) simulated data. The main aim was to assess evidence for both general and specific genetic effects o...
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Open AccessGenome-wide linkage analysis of longitudinal phenotypes using σ2A random effects (SSARs) fitted by Gibbs sampling
The study of change in intermediate phenotypes over time is important in genetics. In this paper we explore a new approach to phenotype definition in the genetic analysis of longitudinal phenotypes. We utilize...