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  1. Article

    Open Access

    Isometric Exercise Training and Arterial Hypertension: An Updated Review

    Hypertension is recognised as a leading attributable risk factor for cardiovascular disease and premature mortality. Global initiatives towards the prevention and treatment of arterial hypertension are centred...

    Jamie J. Edwards, Damian A. Coleman, Raphael M. Ritti-Dias in Sports Medicine (2024)

  2. Article

    Open Access

    Contrast echocardiography: a practical guideline from the British Society of Echocardiography

    Ultrasound contrast agents (UCAs) have a well-established role in clinical cardiology. Contrast echocardiography has evolved into a routine technique through the establishment of contrast protocols, an excelle...

    Reinette Hampson, Roxy Senior, Liam Ring, Shaun Robinson in Echo Research & Practice (2023)

  3. Article

    Open Access

    Real world hospital costs following stress echocardiography in the UK: a costing study from the EVAREST/BSE-NSTEP multi-centre study

    Stress echocardiography is widely used to detect coronary artery disease, but little evidence on downstream hospital costs in real-world practice is available. We examined how stress echocardiography accuracy ...

    Casey L. Johnson, William Woodward, Annabelle McCourt in Echo Research & Practice (2023)

  4. Article

    Open Access

    Validation of a deep-learning-based retinal biomarker (Reti-CVD) in the prediction of cardiovascular disease: data from UK Biobank

    Currently in the United Kingdom, cardiovascular disease (CVD) risk assessment is based on the QRISK3 score, in which 10% 10-year CVD risk indicates clinical intervention. However, this benchmark has limited ef...

    Rachel Marjorie Wei Wen Tseng, Tyler Hyungtaek Rim, Eduard Shantsila in BMC Medicine (2023)

  5. No Access

    Chapter and Conference Paper

    Feature-Conditioned Cascaded Video Diffusion Models for Precise Echocardiogram Synthesis

    Image synthesis is expected to provide value for the translation of machine learning methods into clinical practice. Fundamental problems like model robustness, domain transfer, causal modelling, and operator ...

    Hadrien Reynaud, Mengyun Qiao in Medical Image Computing and Computer Assis… (2023)

  6. No Access

    Article

    Myocardial work and left ventricular mechanical adaptations following isometric exercise training in hypertensive patients

    Hypertension is a major risk factor for cardiovascular disease. Isometric exercise training (IET) reduces resting and ambulatory blood pressure; however, few studies have investigated the myocardial adaptation...

    Jamie M. O’Driscoll, Jamie J. Edwards in European Journal of Applied Physiology (2022)

  7. No Access

    Chapter and Conference Paper

    D’ARTAGNAN: Counterfactual Video Generation

    Causally-enabled machine learning frameworks could help clinicians to identify the best course of treatments by answering counterfactual questions. We explore this path for the case of echocardiograms by looki...

    Hadrien Reynaud, Athanasios Vlontzos in Medical Image Computing and Computer Assis… (2022)

  8. No Access

    Chapter

    Hybrid Cardiac Imaging for the Cardiologist with Expertise in Echocardiography

    Echocardiography is the first-line imaging test in virtually all cardiovascular conditions, due to the advantages of low cost, widespread diffusion, portability, versatility, low environmental footprint, and r...

    Eugenio Picano, Paul Leeson in Hybrid Cardiac Imaging for Clinical Decision-Making (2022)

  9. Article

    Open Access

    Impact of COVID-19 on UK stress echocardiography practice: insights from the EVAREST sites

    Introduction Healthcare delivery is being transformed by COVID-19 to reduce transmission risk but continued delivery of routine clinical tests is essential. Stress echocardiography is one of the most widely used ...

    Cameron Dockerill, William Woodward, Annabelle McCourt in Echo Research & Practice (2021)

  10. No Access

    Chapter and Conference Paper

    Ultrasound Video Transformers for Cardiac Ejection Fraction Estimation

    Cardiac ultrasound imaging is used to diagnose various heart diseases. Common analysis pipelines involve manual processing of the video frames by expert clinicians. This suffers from intra- and inter-observer ...

    Hadrien Reynaud, Athanasios Vlontzos in Medical Image Computing and Computer Assis… (2021)

  11. Article

    Open Access

    The UK Biobank imaging enhancement of 100,000 participants: rationale, data collection, management and future directions

    UK Biobank is a population-based cohort of half a million participants aged 40–69 years recruited between 2006 and 2010. In 2014, UK Biobank started the world’s largest multi-modal imaging study, with the aim ...

    Thomas J. Littlejohns, Jo Holliday, Lorna M. Gibson, Steve Garratt in Nature Communications (2020)

  12. Article

    Open Access

    Trial of Exercise to Prevent HypeRtension in young Adults (TEPHRA) a randomized controlled trial: study protocol

    Hypertension prevalence in young adults has increased and is associated with increased incidence of cerebrovascular and cardiovascular events in middle age. However, there is significant debate regards how to ...

    Wilby Williamson, Odaro J. Huckstep, Eleni Frangou in BMC Cardiovascular Disorders (2018)

  13. Article

    Open Access

    Neonatal autonomic function after pregnancy complications and early cardiovascular development

    Heart rate variability (HRV) has emerged as a predictor of later cardiac risk. This study tested whether pregnancy complications that may have long-term offspring cardiac sequelae are associated with differenc...

    Christina Y. L. Aye, Adam James Lewandowski, Julien Oster, Ross Upton in Pediatric Research (2018)

  14. Article

    Open Access

    P100: Trial of Exercise to Prevent Hypertension in Young Adults (TEPHRA): Rationale and Protocol

    Hypertension or pre-hypertension in young adults is unusual and more often linked with an adverse family or pregnancy history, such as preterm birth, than hypertension which develops later in life1–4. Surprisingl...

    Afifah Mohamed, Odaro Huckstep, Wilby Williamson, Charlotte Herdman in Artery Research (2017)

  15. Article

    Open Access

    Disproportionate cardiac hypertrophy during early postnatal development in infants born preterm

    Adults born very preterm have increased cardiac mass and reduced function. We investigated whether a hypertrophic phenomenon occurs in later preterm infants and when this occurs during early development.

    Christina Y L Aye, Adam J Lewandowski, Pablo Lamata, Ross Upton in Pediatric Research (2017)

  16. No Access

    Article

    Hypertension in pregnancy: a risk factor for the whole family?

    Hypertension in pregnancy is a known risk factor for increased cardiovascular risk for both the mother and her offspring. New findings suggest the offspring of normotensive pregnancies should also be considere...

    Grace Z. Yu, Paul Leeson in Nature Reviews Nephrology (2017)

  17. Article

    Open Access

    Reference ranges for cardiac structure and function using cardiovascular magnetic resonance (CMR) in Caucasians from the UK Biobank population cohort

    Cardiovascular magnetic resonance (CMR) is the gold standard method for the assessment of cardiac structure and function. Reference ranges permit differentiation between normal and pathological states. To date...

    Steffen E. Petersen, Nay Aung in Journal of Cardiovascular Magnetic Resonan… (2017)

  18. Article

    Open Access

    12th WINFOCUS world congress on ultrasound in emergency and critical care

    A1 Point-of-care ultrasound examination of cervical spine in emergency department

    Yahya Acar, Onur Tezel, Necati Salman, Erdem Cevik in Critical Ultrasound Journal (2016)

  19. Article

    Open Access

    Correction: Corrigendum: Comprehensive multi-modality assessment of regional and global arterial structure and function in adults born preterm

    Correction to: Hypertension Research (2016) 39, 39–45; doi:10.1038/hr.2015.102 This article was originally published under a CC BY-NC-ND v4.0 license, but has now been made available under a CC BY 4.0 license....

    Henry Boardman, Katherine Birse, Esther F Davis, Polly Whitworth in Hypertension Research (2016)

  20. No Access

    Article

    Preterm Birth and Hypertension: Is There a Link?

    Factors in perinatal life have recently been recognized as determinants of later life health and diseases, especially hypertension. The detection of higher values of blood pressure in preterm-born individuals ...

    Mariane Bertagnolli, Thuy Mai Luu, Adam James Lewandowski in Current Hypertension Reports (2016)

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