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  1. No Access

    Chapter

    Discovery and Functional Analysis of the Single-Celled Yeast NADPH Oxidase, Yno1

    In this chapter, we describe the discovery of the NADPH oxidase gene and protein of the single-celled yeast Saccharomyces cerevisiae, Yno1. This enzyme was characterized with respect to mechanism of action, subce...

    Michael Breitenbach, Mark Rinnerthaler in NADPH Oxidases Revisited: From Function to… (2023)

  2. Article

    Open Access

    Author Correction: Candida albicans biofilm development is governed by cooperative attachment and adhesion maintenance proteins

    Andrew D. McCall, Ruvini U. Pathirana, Aditi Prabhakar in npj Biofilms and Microbiomes (2021)

  3. Article

    Open Access

    A Rab escort protein regulates the MAPK pathway that controls filamentous growth in yeast

    MAPK pathways regulate different responses yet can share common components. Although core regulators of MAPK pathways are well known, new pathway regulators continue to be identified. Overexpression screens ca...

    Sheida Jamalzadeh, Atindra N. Pujari, Paul J. Cullen in Scientific Reports (2020)

  4. Article

    Open Access

    Candida albicans biofilm development is governed by cooperative attachment and adhesion maintenance proteins

    The opportunistic fungal pathogen Candida albicans is capable of adhering to the oral mucosa despite forces created by salivary flow. Although many fungal adhesion proteins have been identified, less is known abo...

    Andrew D. McCall, Ruvini U. Pathirana, Aditi Prabhakar in npj Biofilms and Microbiomes (2019)

  5. Article

    Open Access

    Colloidal Gels with Tunable Mechanomorphology Regulate Endothelial Morphogenesis

    Endothelial morphogenesis into capillary networks is dependent on the matrix morphology and mechanical properties. In current 3D gels, these two matrix features are interdependent and their distinct roles in e...

    Smruti K. Nair, Sukanya Basu, Ballari Sen, Meng-Hsuan Lin in Scientific Reports (2019)

  6. Article

    Open Access

    Candida albicans Sap6 amyloid regions function in cellular aggregation and zinc binding, and contribute to zinc acquisition

    Candida albicans is an opportunistic fungal pathogen colonizing the oral cavity. C. albicans secreted aspartic protease Sap6 is important for virulence during oral candidiasis since it de...

    Rohitashw Kumar, Christine Breindel, Darpan Saraswat, Paul J. Cullen in Scientific Reports (2017)

  7. No Access

    Chapter and Conference Paper

    Yeast Signal Transduction: Regulation and Interface with Cell Biology

    We examined the morphogenetic transitions that yeast cells undergo in response to extracellular cues, and determined that multiple mechanisms control specificity of signal transduction pathway signaling and th...

    George F. Sprague, Paul J. Cullen, April S. Goehring in Advances in Systems Biology (2004)

  8. No Access

    Chapter

    Regulation of Nitrogen Fixation Genes

    Robert G. Kranz, Paul J. Cullen in Anoxygenic Photosynthetic Bacteria (1995)