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    Article

    St. John’s Wort Modulates the Toxicities and Pharmacokinetics of CPT-11 (Irinotecan) in Rats

    CPT-11 is a DNA topoisomerase I inhibitor for the therapy of colorectal cancer, whereas St. John’s Wort (Hypericum perforatum, SJW) is a widely used herbal anti-depressant. This study aimed to investigate the eff...

    Ze** Hu, **aoxia Yang, Paul Chi-Liu Ho, Eli Chan… in Pharmaceutical Research (2005)