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Article
Open AccessDNA fusion-gene vaccination in patients with prostate cancer induces high-frequency CD8+ T-cell responses and increases PSA doubling time
We report on the immunogenicity and clinical effects in a phase I/II dose escalation trial of a DNA fusion vaccine in patients with prostate cancer. The vaccine encodes a domain (DOM) from fragment C of tetanu...
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Article
Open AccessFainting Fanconi syndrome clarified by proxy: a case report
Rare diseases may elude diagnosis due to unfamiliarity of the treating physicians with the specific disorder. Yet, advances in genetics have tremendously enhanced our ability to establish specific and sometime...
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Article
Open AccessMaternal anemia is a potential risk factor for anemia in children aged 6–59 months in Southern Africa: a multilevel analysis
The effect of maternal anemia on childhood hemoglobin status has received little attention. Thus, we examined the potential association between maternal anemia and childhood anemia (aged 6–59 months) from sele...
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Article
Open AccessTubular iron deposition and iron handling proteins in human healthy kidney and chronic kidney disease
Iron is suggested to play a detrimental role in the progression of chronic kidney disease (CKD). The kidney recycles iron back into the circulation. However, the localization of proteins relevant for physiolog...
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Open AccessPublisher Correction: Tubular iron deposition and iron handling proteins in human healthy kidney and chronic kidney disease
A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has been fixed in the paper.
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Article
Open AccessCrescentic glomerulonephritis with anti-GBM antibody but no glomerular deposition
Anti-glomerular basement membrane (GBM) antibodies are highly specific for Goodpasture’s or anti-GBM disease, in which they are generally directed against the non-collagenous (NC1) domain of the alpha 3 chain ...
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Article
Open AccessMaternal overweight and obesity and the risk of caesarean birth in Malawi
Overweight and obese women are at risk of pregnancy and delivery complications. This study investigates the trend and association between maternal overweight and obesity on caesarean births in Malawi.
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Article
Open AccessKaryomegalic interstitial nephritis with a novel FAN1 gene mutation and concurrent ALECT2 amyloidosis
Karyomegalic interstitial nephritis (KIN) is a rare hereditary cause of chronic kidney disease. It typically causes progressive renal impairment with haemoproteinuria requiring renal replacement therapy before...
