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  1. Article

    Open Access

    The ATP-binding cassette transporter A1 regulates phosphoantigen release and Vγ9Vδ2 T cell activation by dendritic cells

    Vγ9Vδ2 T cells are activated by phosphoantigens, such as isopentenyl pyrophosphate (IPP), which is generated in the mevalonate pathway of antigen-presenting cells. IPP is released in the extracellular microenv...

    Barbara Castella, Joanna Kopecka, Patrizia Sciancalepore in Nature Communications (2017)