24 Result(s)
within
Patrick T. Bradshaw
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Article
Open AccessBody composition and cancer survival: a narrative review
Interest in understanding the relationship between body composition and cancer survival has remained strong for decades, with a number of recent systematic reviews on the topic. However, the current state of e...
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The association between the Mediterranean Diet Score and death from cancer of the head and neck
The association between diet quality, captured by the Mediterranean Diet Score (MDS), and mortality was studied among 1184 individuals diagnosed with head and neck cancer (HNC) who reflected on the year preced...
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Article
Open AccessDevelopment and validation of prediction models for gestational diabetes treatment modality using supervised machine learning: a population-based cohort study
Gestational diabetes (GDM) is prevalent and benefits from timely and effective treatment, given the short window to impact glycemic control. Clinicians face major barriers to choosing effectively among treatme...
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Diabetes and cardiovascular disease mortality among a population-based cohort of women with and without breast cancer
We investigated whether the relationship between diabetes and all-cause and CVD-related mortality differed between women with and without breast cancer among a cohort drawn from the same source population.
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Article
Open AccessInteraction between known risk factors for head and neck cancer and socioeconomic status: the Carolina Head and Neck Cancer Study
Prior studies of squamous cell carcinoma of the head and neck (SCCHN) have explored the effect of socioeconomic status (SES) as an independent risk factor; however, none have investigated the interaction of kn...
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Article
Air Pollution and Breast Cancer: a Review
Breast cancer is the most common cancer diagnosed among US women. Air pollution is a pervasive mixture of chemicals containing carcinogenic compounds and chemicals with endocrine-disrupting properties. In the ...
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Article
Pre-diagnostic aspirin use and mortality after breast cancer
Whether aspirin or other nonsteroidal anti-inflammation drug (NSAID) use is associated with mortality following breast cancer remains unclear. Consideration o...
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Open AccessModification of the association between recreational physical activity and survival after breast cancer by promoter methylation in breast cancer-related genes
Mechanisms underlying the inverse association between physical activity and survival after breast cancer are unresolved, but DNA methylation may play a role. We hypothesized that promoter methylation of breast...
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Article
Polycystic ovarian syndrome (PCOS), related symptoms/sequelae, and breast cancer risk in a population-based case–control study
Despite the overlap between the clinical symptoms/sequelae of polycystic ovarian syndrome (PCOS) and many known reproductive risk factors for breast cancer, the relationship between PCOS and breast cancer rema...
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Article
DNA methylation modifies the association between obesity and survival after breast cancer diagnosis
Mechanisms underlying the poor breast cancer prognosis among obese women are unresolved. DNA methylation levels are linked to obesity and to breast cancer survival. We hypothesized that obesity may work in con...
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Article
Open AccessLatent class analysis suggests four distinct classes of complementary medicine users among women with breast cancer
Breast cancer patients commonly report using >1 form of complementary and alternative medicine (CAM). However, few studies have attempted to analyze predictors and outcomes of multiple CAM modalities. We sough...
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Article
Vitamin D-related gene polymorphisms, plasma 25-hydroxyvitamin D, and breast cancer risk
Studies of vitamin D-pathway genetic variants in relation to cancer risk have been inconsistent. We examined the associations between vitamin D-related genetic polymorphisms, plasma 25-hydroxyvitamin D [25(OH)...
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Article
Risk Factors for Serrated Polyps of the Colorectum
Serrated pathway polyps are a relatively new area of interest in the field of colorectal cancer screening and prevention. Akin to conventional adenomas, some serrated polyps (SPs) have the potential to develop...
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Post-diagnosis physical activity and survival after breast cancer diagnosis: the Long Island Breast Cancer Study
Physical activity (PA) is associated with physiological responses thought to beneficially affect survival after breast cancer diagnosis, yet few studies have considered the entire survivorship experience. Effe...
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Article
Genetic variation in multiple biologic pathways, flavonoid intake, and breast cancer
We previously reported an inverse association between flavonoid intake and breast cancer incidence, which has been confirmed by others, but no studies have considered simultaneously potential interactions of f...
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Article
Polymorphisms in oxidative stress genes, physical activity, and breast cancer risk
The mechanisms driving the physical activity–breast cancer association are unclear. Exercise both increases reactive oxygen species production, which may transform normal epithelium to a malignant phenotype, a...
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Article
Genetic polymorphisms in telomere pathway genes, telomere length, and breast cancer survival
The impact of genetic variants in telomere pathway genes on telomere length and breast cancer survival remains unclear. We hypothesized that telomere length and genetic variants of telomere pathway genes are a...
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Article
Prognostic significance of gene-specific promoter hypermethylation in breast cancer patients
The association between promoter methylation status and survival was investigated in a large cohort of women with breast cancer, participants in the Long Island Breast Cancer Study Project. Archived tumor tiss...
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Article
Gene promoter methylation is associated with increased mortality among women with breast cancer
To better understand breast cancer etiology and progression, we explored the association between promoter methylation status of three breast cancer-related genes (BRCA1, APC, and p16) and survival in a large coho...
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Article
Oral health and risk for head and neck squamous cell carcinoma: the Carolina Head and Neck Cancer Study
Recent reports have linked oral health and periodontal disease indicators with increased risk of squamous cell carcinoma of head and neck (SCCHN). Thus far, evidence has been inconclusive; our objective was to...
