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  1. Article

    Open Access

    The formation of estrogen-like tamoxifen metabolites and their influence on enzyme activity and gene expression of ADME genes

    Tamoxifen, a standard therapy for breast cancer, is metabolized to compounds with anti-estrogenic as well as estrogen-like action at the estrogen receptor. Little is known about the formation of estrogen-like ...

    Janina Johänning, Patrick Kröner, Maria Thomas, Ulrich M. Zanger in Archives of Toxicology (2018)