3 Result(s)
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Patricia L. Mitchell
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Article
Open AccessImpact of the gut microbiota and associated metabolites on cardiometabolic traits, chronic diseases and human longevity: a Mendelian randomization study
Features of the gut microbiota have been associated with several chronic diseases and longevity in preclinical models as well as in observational studies. Whether these relations underlie causal effects in hum...
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Article
Open AccessMendelian randomization prioritizes abdominal adiposity as an independent causal factor for liver fat accumulation and cardiometabolic diseases
Observational studies have linked adiposity and especially abdominal adiposity to liver fat accumulation and non-alcoholic fatty liver disease. These traits are also associated with type 2 diabetes and coronar...
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Article
Protectin DX alleviates insulin resistance by activating a myokine-liver glucoregulatory axis
Lower levels of ω–3 fatty acid–derived resolution mediators have been linked to insulin resistance in obese mice. André Marette and his colleagues now show that treatment of obese mice with a resolution mediat...
